摘要
目的:探讨口腔鳞状细胞癌在颈部淋巴结的包膜外侵犯(ECS)在各淋巴结分区的浸润方向的差异性。方法:纳入术后病理证实颈部淋巴结转移阳性患者57例。对淋巴结ECS方向的差异性及ECS与病灶T分级、浸润厚度、分化程度,淋巴结大小等之间的关系进行相关分析。结果:57例患者中,30例发生ECS,发生ECS的淋巴结共78个(转移阳性淋巴结共174个),ECS在淋巴结浅面的发生频次为66,深面为51。其中Ⅰ区发生ECS者29个淋巴结,浅面ECS频次为26,深面为13(P<0.05)。其他各区ECS的浸润方向差异无显著性。ECS发生率与原发灶T分期无明显相关性(P>0.05);与原发灶浸润厚度(P<0.05)、肿瘤分化程度(P<0.05)及淋巴结直径(P<0.01)相关。结论:口腔鳞癌颈部Ⅰ区淋巴结浅面发生ECS的概率较深面大。颈淋巴结ECS的发生率与口腔癌肿瘤浸润厚度、淋巴结直径正相关,与肿瘤分化程度负相关。
Objective：To study the direction of cervical node extracapsular spread（ECS）of oral squamous cell carcinoma（OSCC）. Methods：57 cases of OSCC were treated by combined radical operation.The relationship between ECS and T stage,tumor thick-ness,differentiation degree of OSCC,lymph node size and the ECS direction in each lymph node level were statistically analysed. Results：ECS was found in 30 of the 57 cases,and in 78 of the 174 metastasis positive lymph nodes.29 ECS nodes in levelⅠ,the frequency of the shallow side was 26,the deep side 13（P=0.000 3）.But the difference in other levels was not statistically signifi-cant（P〉0.05）.It was not statistically significant between the incidence of ECS and T stage;it was statistically significant between the incidence of ECS and tumor thickness（P〈0.05）,tumor differentiation degree（P〈0.05）and the lymph node size（P〈0.01）. Conclusion：ECS of OSCC on the shallow side is more than that in the deep side of lymph nodes in levelⅠ.ECS is positively corre-lated with the tumor thickness of OSCC,metastasied lymph node size;negatively related to the differentiation degree of OSCC.
出处
《实用口腔医学杂志》
CAS
CSCD
北大核心
2014年第5期676-679,共4页
Journal of Practical Stomatology
关键词
口腔癌
淋巴结转移
包膜外侵犯
侵犯方向
分化程度
肿瘤浸润厚度
淋巴结
Oral squamous cell carcinoma
Lymph node metastasis
Spread direction
Differentiation degree
Tumor thickness
Lymph node size
