摘要
目的探讨修改版昏迷恢复量表(CRS-R)对意识障碍患者预后的评估价值。方法对29例重症脑部病变意识障碍患者进行CRS-R评分,根据评分分为植物状态(VS)和最小意识状态(MCS)。在患者出院≥3个月后进行格拉斯哥结局量表(GOS)评分;并对两个量表评分的相关性进行分析。结果本组VS患者20例、MCS患者9例,二者CRS-R评分分别为(5.15±2.35)分和(11.88±4.01)分。VS患者GOS评分≤3分(预后差)的比率(95%,19/20)显著高于MCS患者(44.4%,4/9)(P<0.05)。Pearson相关分析显示,CRS-R评分与GOS评分呈正相关(r=0.558,P<0.05)。CRS-R评分的子项中,运动、言语和交流与GOS评分呈正相关(r=0.663,r=0.637,r=0.424,均P<0.05);而听觉、视觉和唤醒度与GOS评分无关。结论意识障碍患者CRS-R评分越高,预后越好。
Objective To explore the assessable value of coma recovery scale-revised （CRS-R） on prognosis in patients with disorders of consciousness.Methods Twenty-nine patients with disorders of consciousness caused by severe brain lesions were scored by CRS-R,and they were divided into vegetative state （VS） and minimally conscious state （MCS） according to the scores.Glasgow outcome scale （GOS） were scored in the patients at ≥3 months after discharge.The correlation between the two scales was analyzed.Results There were 20 VS patients and 9 MCS patients in this group,with CRS-R scores were （5.15 ±2.35） and （11.88 ±4.01） respectively.The rate of GOS score ≤3 （poor prognosis） in VS patients （95％,19/20） was significantly higher than that in MCS patients （44.4％,4/9） （P ＜ 0.05）.Pearson correlation analysis showed that CRS-R score was positively correlated with GOS score （r =0.558,P ＜ 0.05）.In the subprojects of CRS-R score,movement,speech and communication were positively correlated with GOS score （r =0.663,r =0.637,r =0.424,all P ＜ 0.05） ; while hearing,vision and arousal were not related to GOS score.Conclusion In patients with disorders of consciousness,the CRS-R score higher,the prognosis better.
出处
《临床神经病学杂志》
CAS
北大核心
2014年第5期370-371,共2页
Journal of Clinical Neurology
基金
国家自然科学基金(81271548)
广东省科技计划[2012(A)030400025]
