摘要
目的分析不同体质的中风先兆证(PAS)患者发生脑梗死的风险,为开展PAS体质干预研究提供参考。方法对75例PAS患者采用ABCD2评分,按分值分为低危组(0~3分)、中危组(4~5分)和高危组(6~7分),并用"中医体质量表"对患者进行体质判定,观察不同体质、不同风险患者第2天及第7天的脑梗死发生率。结果 PAS患者体质以痰湿质、阴虚质多见,分别为32.00%、24.00%;患者第2天及7天内进展为脑梗死者分别为8例及13例,7天脑梗死发生率为17.33%;不同卒中风险分级的7天内脑梗死发生率比较,差异有统计学意义(P<0.05);不同体质7天内脑梗死发生率比较,差异无统计学意义(P>0.05),发生率以痰湿质最高为25.00%,其次是阴虚质为16.67%;痰湿质、阴虚质与ABCD2评分呈正相关(P<0.05),平和质与其呈负相关(P<0.05)。结论不同体质的PAS患者可能存在不同的脑梗死风险,痰湿质最高,其次是阴虚质,临床可针对患者体质开展PAS的干预。
Objective To analyze the cerebral infarction risk of premonitory apoplexy syndrome （PAS） patients with different TCM institutions so that to provide reference for PAS constitution intervention research. Methods ABCD2 score was adopted for 75 PAS patients included in the study. The patients were grouped into low-risk （0 -3 ）, moderate-risk （4 -5） and high-r/sk （6 -7） according to the scores. The institutions were distinguished by TCM constitution questionnaire. The occurrence rate of cerebral infarction of patients with different constitutions and risks on the 2nd and 7th day were observed. Results Phlegm-damp （32. 00% ） and yin-deficiency （24. 00% ） constitution were mostly seen in PAS patients. There were 8 cases developed into cerebral infarction on the 2nd day and 13 cases developed into cerebral infarction within 7 days. The occurrence rate in 7 days was 17.33%. There was a statistical significance between different risk levels in the occurrence of cerebral infarction within 7 days （ P 〈 0. 05 ）. There was no statistical significance between different constitutions in the occurrence of cerebral infarction within 7 days （P 〉 0. 05）. But patients with phlegm-dampness constitution had the highest occurrence rate （25.00%） and followed by patients with yin-deficiency constitution （ 16. 67% ）. There existed a positive correlation between phlegm-dampness and yin-deficiency constitution and ABCD2 score （ P 〈 0. 05 ） and a negative correlation between normal constitution and ABCD2 score （P 〈 0. 05 ）. Conclusion PAS patients with different constitutions may have different cerebral infarction risks. Patients with phlegm-damp constitution have the highest risk and followed by patients with yindeficiency constitution. Therefore, PAS intervention therapy can be made in clinic according to patient＇s constitution.
出处
《中医杂志》
CSCD
北大核心
2014年第21期1845-1848,共4页
Journal of Traditional Chinese Medicine
基金
陈可冀中西医结合发展基金资助项目(CKJ2011021)
关键词
中风先兆
中医体质
ABCD2评分
脑梗死
premonitory apoplexy
constitution of Chinese Medicine： ABCD2 score ： cerebral infarction
