摘要
目的探讨睾丸酮丛毛单胞菌的药敏及临床治疗情况。方法回顾分析2011年12月-2013年12月睾丸酮丛毛单胞菌药敏试验结果及病人临床资料。结果共分离出15株睾丸酮丛毛单胞菌,其中11例病人为医院感染;15株睾丸酮丛毛单胞菌中对替加环素(15/15)、亚胺培南(13/15)、哌拉西林/他唑巴坦(10/15)、左旋氧氟沙星(10/15)较敏感,对氨苄西林(5/15)、头孢唑啉(5/15)、氨曲南(6/15)、环丙沙星(6/15)敏感性较低,其中有5株为多重耐药株;治疗睾丸酮丛毛单胞菌所致的感染,以β-内酰胺类抗生素治疗为主,严重感染病人使用复合制剂或联合用药,其中11例病人治愈。结论睾丸酮丛毛单胞菌引起的感染较为少见,多数为医院感染且患者有严重的基础疾病;临床应根据药敏试验结果选择敏感抗菌药物,以有效控制该菌引起的感染。
Objective To investigate the drug resistance of Cornamonas testosteroni and the condition of clinical treatment. Methods Retrospective analysis was made on the results of antibiotic susceptibility test of Comamonas testosteroni and clinical data from december, 2011 to december, 2013. Results 15 C. testosteroni clinical isolates were collected, of whom 11 were from nosocomial infection. These 15 isolates were more sensitive to tigecyeline （ 15/15 ）, imipenem （ 13/15 ）, Piperacillin/ tazobactam（10/15） and levofloxacin（10/15）, however, they were less sensitive to ampicillin（5/15）, cefazolin（5/15）, aztreonam（6/15 ） and ciprofloxacin （6/15）. 5 isolates were multi -drug resistant. 13 -lactam were the main antibiotics used in curing C. testosteroni caused infection, compound preparation or combination drug were used in curing those patients with severe infection. 11 patients were recovered at last. Conclusion Infection caused by C. testosterone is rare, most of them are nosocomial infections and accompany with severe basic disease. Sensitive antibiotics should be chosen based on the results of antibiotic susceptibility test to control infections caused by C. testosteroni effectively.
出处
《中国卫生检验杂志》
北大核心
2014年第21期3170-3171,3174,共3页
Chinese Journal of Health Laboratory Technology
关键词
睾丸酮丛毛单胞菌
药敏试验
临床信息
抗生素
Comamonas testosterone
Drug sensitiveness test
Clinical information
Antibiotic
