摘要
目的探讨右美托咪定应用于高龄患者腰硬联合麻醉下行前列腺电切术的效果。方法选取在腰硬联合麻醉下行前列腺电切术的高龄患者100例，分为试验组和对照组各50例。腰硬联合麻醉后试验组患者即刻给予0．8～1μ/gkg的右美托咪定缓慢静脉输注，对照组则不使用。观察并记录两组患者麻醉前以及麻醉后10min、30min、60min、术毕的生命体征、寒战以及术后24h内不良反应的发生情况。结果在麻醉后的不同时间点，试验组患者的平均动脉压、心率以及寒战发生率和分级均明显低于对照组患者（P〈0．05），两组患者的血氧饱和度以及其他不良反应差异无统计学意义（P〉0．05）。结论右美托咪定能够降低高龄患者腰硬联合麻醉下行前列腺电切术时寒战的发生率及发生频率，不影响呼吸功能，且不加重不良反应。
Objective To explore the effect of application of dexmedetomidine in combined spinal-epidural anesthesia tor prostate electrocision in elderly patients. Methods One hundred elderly patients who underwent the prostate electrocision under com- bined spinal-epidural anesthesia were randomly divided into experimental and control groups,50 cases in each group. The experimental group was immediately given 0. 8 - 1 ~g/kg of dexmedetomidine through slow intravenous infusion after combined spinal-cpidural anes- thesia,while it was not used in the control group. The vital signs were compared before and after 10 min,30 rain and 60 min of anesthe- sia as well as shiver and adverse reactions within 24 h after operation were compared between the two groups. Results The average ar- terial pressure, heart rate and incidence rate, and grading of shivering in the experimental group were significantly lower than that in the control group （P 〈 0. 05 ）. However, there was no significant difference in blood oxygen saturation and other adverse reactions between the two groups. Conclusion Dexmedetomidine can obviously reduce the incidence rate and frequency of chill in combined spinal-epi- dural anesthesia for prostate electrotomy in elderly patients but does not influence respiratory function and increase adverse reactions.
出处
《实用医院临床杂志》
2014年第6期60-62,共3页
Practical Journal of Clinical Medicine
关键词
右美托咪定
前列腺电切术
高龄
腰硬联合麻醉
Dexmedetomidine
Prostate electrocision
Aged
Combined spinal-epidural anesthesia
