摘要
多囊卵巢综合征(polycystic ovary syndrome,PCOS)是以高雄激素血症为主要特征的内分泌代谢紊乱性疾病,是生殖内分泌领域研究的热点和难点课题之一。近年来大量研究显示,PCOS患者普遍处于一种慢性低度炎症状态,并且这种炎症环境与高雄激素血症的发展密切相关,或者高雄激素血症诱导炎症产生,亦或炎症刺激卵巢产生高雄激素血症,两者相互影响,共同促进PCOS的发生、发展。
Polycystic ovary syndrome (PCOS) is a disease of endocrine and metabolic disorder, which is mainly characterized by hyperandrogenism. It has always been the hot and difficult topic in the reproductive endocrine field. Recently, a large number of studies have shown that PCOS is a chronic low-grade inflammation. Moreover, there is a co-relationship between this inflammation and hyperandrogenism: either the hyperandrogenism inducing the inflammation, or the inflammation stimulating the ovary to produce more androgen. They may influence each other, and promote the occurrence and development of PCOS together.
出处
《生殖与避孕》
CAS
CSCD
2014年第11期936-939,共4页
Reproduction and Contraception
基金
青年科学基金项目
项目号:81001535
上海市科委引导项目
项目号为KW-201346919