摘要
非酒精性脂肪性肝病(NAFLD)和胆石症(GD)是代谢综合征在肝胆系统中的表现,二者与胰岛素抵抗、肥胖、血脂异常、血糖异常等密切相关。回顾了国内外的研究,发现胰岛素抵抗、肥胖、血脂紊乱、血糖异常、中老年、女性是NAFLD和GD的共同高危因素。NAFLD是GD患病的危险因素,GD与非酒精性脂肪性肝炎和肝纤维化密切相关,GD促进NAFLD的进展。从而认为防治NAFLD可降低GD的发病率,防治GD可减缓NAFLD的进展。
Nonalcoholic fatty liver disease （NAFLD）and gallstone disease （GD）are considered the manifestations of metabolic syndrome in the liver and gallbladder.NAFLD and GD are closely related to insulin resistance （IR）,obesity,dyslipidemia,abnormal glucose metabo-lism,and so on.Worldwide studies,which have been reviewed,show that both NAFLD and GD have the common risk factors,such as IR, obesity,dyslipidemia,abnormal glucose metabolism,and middle-aged and elderly women.NAFLD is the risk factor for GD.GD,closely related to nonalcoholic steatohepatitis and liver fibrosis,accelerates the progression of NAFLD.Thus,it is considered that the prevention and treatment of NAFLD can reduce the incidence of GD,and the progression of NAFLD can be delayed by the prevention and treatment of GD.
出处
《临床肝胆病杂志》
CAS
2014年第11期1217-1220,共4页
Journal of Clinical Hepatology
关键词
脂肪肝
胆结石
代谢综合征X
胰岛素抵抗
综述
fatty liver
cholelithiasis
metabolic syndrome X
insulin resistance
review
