摘要
目的探讨磁共振全身成像技术(WB-DWI)在良恶性淋巴结鉴别中的应用价值。方法收集2008年9月至2012年12月间43例经临床和病理证实的良性和恶性淋巴结肿大的患者和同期的20例健康志愿者分别行WB-DWI检查。分析良性、恶性淋巴结的WB-DWI表现和ADC值差异。结果健康志愿者WB-DWI淋巴结表现为类圆形或椭圆形较高信号,短径不超过1.0 cm,按照一定的解剖部位呈规律分布;ADC值(2.24±0.56)×10-3mm2/s。良性淋巴结呈类圆形,短径不超过2.0 cm,较正常淋巴结信号增高,较少融合;平均ADC值(1.57±0.32)×10-3mm2/s。恶性淋巴结不同程度增大、可融合,分布无规律;平均ADC值(1.57±0.32)×10-3mm2/s。健康志愿者、良性和恶性淋巴结的ADC值之间差异均具有统计学意义(P<0.05)。结论 WB-DWI可以为初步鉴别良恶性淋巴结提供依据,尤其对于某些原发灶不明且伴有淋巴结转移的恶性肿瘤患者具有较大意义。
Objective To investigate the application value of whole-body magnetic resonance imaging（WB-DWI） in the identification of benign and malignant lymph nodes. Methods Twenty healthy volunteers and 43 patients confirmed as benign and malignant lymph nodes clinically and pathologically were collected, and performed WB-DWI examination scan from September 2008 to December 2012. The differences of WB-DWI and ADC values between benign and malignant lymph nodes were analyzed. Results The WB-DWI performance of lymph nodes in healthy volunteers showed class round or oval higher signal, with short diameter less than 1.0 cm and regular distribution according to certain anatomical sites. The average ADC values was（2.24±0.56）×10^-3mm^2/s. Benign lymph nodes showed class circular, with short diameter less than 2.0 cm, and its signs was higher than normal lymph node signal,with less fusion. The average ADC values was（1.57±0.32）×10^-3mm^2/s. Malignant lymph nodes were enlarged to varied extent, with fusion and irregular distribution, and the average ADC values was（1.57±0.32）×10^-3mm^2/s. There were statistically significant differences in ADC values among healthy volunteers, benign and malignant lymph nodes（P〈0.05）.Conclusion WB-DWI scan can provide the basis for preliminary identification of benign and malignant lymph nodes,especially for some malignant tumors of unknown primary tumors associated with lymph node metastasis.
出处
《海南医学》
CAS
2014年第22期3330-3332,共3页
Hainan Medical Journal
基金
海南省自然科学基金(编号:30847
813209
812154)
关键词
淋巴结
全身弥散加权成像
鉴别
筛查
Lymph nodes
Whole-body magnetic resonance imaging（WB-DWI）
Identification
Screening
