摘要
目的:观察有创机械通气后引起医院获得性肺炎中呼吸机相关肺炎患者的主要致病菌。方法:选择55例患者分别在气管插管或切开机械通气后的不同时间,即:小于2 d、2 d后、拔管前,分析深部支气管分泌物细菌培养与药敏结果。结果:采集的129例标本中,有86例细菌培养阳性。共分离出细菌112株,其中革兰阴性杆菌占91.07%,以铜绿假单胞菌、鲍曼不动杆菌、大肠埃希菌、不动杆菌等为主,分别占39.28%、23.21%、7.14%、5.58%,为院内感染的主要致病菌,具有多耐药性及高耐药率。结论:有创机械通气易引起下呼吸道感染,导致医院获得性肺炎或呼吸机相关肺炎。因此,监测致病菌和及时药物敏感试验,有利于临床抗生素的选择及合理使用,从而降低院内感染和死亡率。
Objective：To observe the invasive mechanical ventilation major pathogens causing hospital-acquired pneumonia in patients with ventilator-associated pneumonia.Method：55 patients were intubated at a different time or cut after mechanical ventilation, ie： less than two days, two days later, before extubation, deep bronchial secretions bacterial culture and drug sensitivity were analysed.Result：A total of 129 cases collected specimens,there were 86 cases 112 were isolated from bacteria,of bacterial culture positive,including Gram-negative bacilli accounted for 91.07%, pseudomonas aeruginosa, acinetobacter baumannii, colon dilute egypt bacteria, acinetobacter, etc,accounting for 39.28%, 23.21%, 7.14%, 5.58% separately.They were the main pathogens of nosocomial infections with multidrug resistance and high resistance rates.Conclusion：Invasive mechanical ventilation can lead to lower respiratory tract infection, which led to hospital-acquired pneumonia or ventilator-associated pneumonia in patients with severe illness.Therefore, the monitoring of pathogens and timely drug susceptibility testing in clinical is conducive to the rational use of antibiotics,so as to reduce nosocomial infections and mortality.
出处
《中国医学创新》
CAS
2014年第34期55-58,共4页
Medical Innovation of China
基金
衡阳市科学技术局科技计划一般项目(ks10)
关键词
ICU
机械通气
病原微生物
医院获得性肺炎中呼吸机相关肺炎
Intensive care unit
Mechanical ventilation
Pathogenic microorganisms
Hospital-acquired pneumonia in ventilator-associated pneumonia
