摘要
目的调查大庆地区汉族人群18个STR基因座的遗传多态性。方法应用DNATyper TM19试剂盒检测221名大庆地区汉族无关个体18个STR基因座的等位基因频率,并应用统计软件计算群体遗传学参数。结果 18个STR基因座的基因型分布均符合Hardy-Weinberg平衡(P>0.05),18个基因座的杂合度(H)在0.608~0.896之间,匹配概率(Pm)在0.016~0.196之间,个体识别概率(DP)在0.804~0.984之间,多态信息含量(PIC)在0.560~0.910之间,非父排除概率(PE)值在0.301~0.788之间。结论 18个STR基因座在大庆汉族人群中有较高的多态性,所得的群体遗传学数据可为大庆地区刑事案件的法医学的个体识别、亲权鉴定和群体遗传学研究提供基础数据。
Objective To investigate the polymorphism of 18 STR loci in Han population from Daqing district. Methods DNATyperTM 19 kit was used to detect the allelic frequencies of 18 STR loci in 221 unrelated Daqing Han individuals, and then the population genetics parameters were calculate by using statistic software. Results The results demonstrated that all loci were found to be no deviation from Hardy-Weinberg equilibrium （P^0.05）, Heterozygosity （H） ranged from 0. 608 to 0. 896, matching probability （Pm） ranged from 0. 016 to 0. 196, power of discrimination （DP） ranged from 0. 804 to 0. 984, polymorphism information content （PIC） ranged from 0. 560 to 0. 910, power of exclusion （PE） ranged from 0. 301 to 0. 788. Conclusions The 18 STR loci are relatively abundant in polymorphic information and suitable for forensic personal identification and paternity tes ting.
出处
《刑事技术》
2014年第6期44-46,共3页
Forensic Science and Technology
