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核苷酸类抗乙肝病毒药物致范可尼综合征 被引量：10

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摘要 口服抗乙肝病毒核苷（酸）类似物主要包括核苷类似物及核苷酸类似物，前者包括拉米夫定、恩替卡韦、替比夫定等，后者包括阿德福韦酯（ ADV）、替诺福韦（ TFV）等。核苷酸类药物由肾小球滤过后以原形由肾小管主动分泌排出体外，易在近端肾小管上皮细胞内蓄积，从而产生肾毒性［1－2］。
作者 边赛男 刘晓清 侍效春 夏维波
机构地区 中国医学科学院北京协和医学院北京协和医院感染内科 中国医学科学院北京协和医学院北京协和医院内分泌科
出处 《中华医学杂志》 CAS CSCD 北大核心 2014年第47期3790-3792,共3页 National Medical Journal of China
关键词 抗乙肝病毒药物 核苷酸类似物 范可尼综合征 核苷(酸)类似物 肾小管上皮 核苷酸类药物 核苷类似物 阿德福韦酯
分类号 R979.1 [医药卫生—药品]
  • 相关文献

参考文献30

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二级参考文献82

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共引文献588

同被引文献71

  • 1Zhang, Yu,Zhou, Jian-Hua,Yin, Xiao-Ling,Wang, Feng-Yu.Treatment of hepatitis B virus-associated glomerulonephritis:A meta-analysis[J].World Journal of Gastroenterology,2010,16(6):770-777. 被引量：38
  • 2高瑞通,郑法雷.近端肾小管多种功能缺陷——范可尼综合征的诊治[J].世界医学杂志,2004,8(13):15-18. 被引量：2
  • 3张鸿飞,朱世殊,杨晓晋,徐志强,董漪,陈大为,赵景民,陈菊梅,张太和.小儿乙、丙型肝炎临床与病理研究[J].传染病信息,2006,19(3):130-131. 被引量：25
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引证文献10

二级引证文献23

中华医学杂志
2014年 第47期

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