摘要
目的:通过对心、肾功能正常的失血性休克患者早期液体复苏过程中N末端B型钠尿肽原(NTproBNP)检测,探讨NT-proBNP在休克早期液体复苏中的意义。方法:快速NT-proBNP测定:采用罗氏心梗心衰检测仪cobas h 232Cardiac System分析仪,观测39例休克患者来院后血清中NT-proBNP浓度在补液开始0、2、4、6h的动态变化及其与血压变化的关系。结果:液体复苏后的6h内,随着血压的恢复,NT-proBNP逐渐升高;从开始时的正常值范围(147.33±21.69)μg/L升高到6h后的(402.18±20.37)μg/L。结论:失血性休克初期血清中NT-proBNP浓度升高并与血压恢复成正相关。
Objective：This study was designed to detect the concentration of NT-proBNP and to investigate the significance of NT-proBNP（N-terminal pro-brain natriuretic peptide）during early fluid resuscitation of the patients with hemorrhage shock but without kidney and cardiac dysfunction.Method：The relationship between dynamic changes of NT-proBNP and blood pressure in 39 patients with cobas h 232 Cardiac System analysis instrument was analyzed.At the point of 0,2,4,6hour after fluid resuscitation,the NT-proBNP was measured through rapid determination.Result：In the early 6hours of fluid resuscitation,NT-proBNP raised gradually with the recovery of blood pressure.It＇s concentration raised from a normal level（147.33±21.69）μg/L to（402.18±20.37）μg/L within 6hours.Conclusion：NT-proBNP raised and had a positive correlation with the recovery of blood pressure during early period of shock in patients without kidney and cardiac dysfunction.
出处
《临床急诊杂志》
CAS
2014年第12期741-743,共3页
Journal of Clinical Emergency
基金
2012年佛山市科技局医学类科技攻关项目(No:201208072)
