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289例儿童肺炎支原体感染及其耐药情况分析 被引量:10

Analysis of Mycoplasma pneumonia infection and associated drug resistance in 289 children
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摘要 目的分析我院呼吸道感染患儿肺炎支原体(Mycoplasma pneumoniae,MP)感染情况及其对常用抗生素的耐药性。方法选取2011年1月至2013年12月我科治疗的289例呼吸道感染患儿为研究对象,记录静脉血检测MP抗体Ig M阳性率,并对阳性患儿进行痰培养鉴定,观察并记录药敏试验结果。结果 289例急性呼吸道感染患儿咽拭子支原体培养检测阳性75例(26.0%),低于1岁、1~3岁、3~6岁、6~12岁呼吸道感染患儿支原体培养阳性率差异均无统计学意义(P〉0.05)。MP对强力霉素、美满霉素、阿奇霉素、左氧氟沙星、司帕沙星敏感性较高,而对交沙霉素、克拉霉素、罗红霉素、氧氟沙星呈不同程度的耐药。结论呼吸道感染患儿MP感染率较高,应进行痰培养及药敏试验,选用敏感抗生素,减少耐药株出现。 Objective To investigate the distribution of children Mycoplasma pneumonia(MP) infection in our hospital,and to analyze the drug resistance of MP. Methods From January, 2011 to December 2013, 289 children with respiratory tract infection were selected in our hospital. MP-Ig M test and sputum samples were collected for MP cultivation identification and drug sensitive test was conducted. Results Among 289 children with respiratory infection, 75 cases of MP-Ig M test were positive with a positive rate of 26.0%. There was no significant difference in the positive rate of MP Ig-M among children of ≤1 years old, 1~3 years old, 3~6 years old, and 6~12 years old(P〉0.05). Drug sensitive test showed that MP was sensitive to doxycycline, minocycline, azithromycin, levofloxacin, and sparfloxacin and insensitive to josamycin, clarithromycin, roxithromycin and ofloxacin. Conclusion With higher incidence of children MP infection, MP-Ig M test, sputum samples culture and drug sensitivity test should be taken in time to reduce the drug resistance
作者 苏蓓
出处 《海南医学》 CAS 2015年第1期114-116,共3页 Hainan Medical Journal
关键词 儿童 肺炎支原体 药敏试验 Children Mycoplasma pneumonia Drug sensitivity test
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  • 1韩旭,辛德莉.肺炎支原体对大环内酯类抗生素的耐药机制[J].实用儿科临床杂志,2006,21(16):1101-1103. 被引量:47
  • 2胡亚美 江载芳 诸福棠.实用儿科学[M]第7版[M].北京:人民卫生出版社,2002.1900.
  • 3刘铁英,韩晓华.肺炎支原体P1基因多态性分析现状[J].国际儿科学杂志,2007,34(6):450-452. 被引量:3
  • 4Jacques Gaillat,Antoine Flahault,Bertille Barbeyrac,Jeanne Orfila,Henri Portier,Jean-Pierre Ducroix,Christiane Bébéar,Charles Mayaud.Community epidemiology of Chlamydia and Mycoplasma pneumoniae in LRTI in France over 29 months[J]. European Journal of Epidemiology . 2005 (7)
  • 5Chen ZR,Yan YD,Wang YQ,et al.Epidemiology of communityacquired Mycoplasma Pneumoniae respiratory tract infections among hospitalized Chinese children,including relationships with meteorological factors. Hippokratia . 2013
  • 6Kaluzewski S,Rastawicki W.Seroprevalence of Mycoplasma pneumoniae in Poland in 2008-2013. Medycyna Doswiadczalna i Mikrobiologia . 2014
  • 7Florian Daxboeck,Gelas Khanakah,Claudia Bauer,Maria Stadler,Hanns Hofmann,Gerold Stanek.??Detection of Mycoplasma pneumoniae in serum specimens from patients with mycoplasma pneumonia by PCR(J)International Journal of Medical Microbiology . 2005 (4)
  • 8Wujun Jiang,Yongdong Yan,Wei Ji,Yuqing Wang,Zhengrong Chen.??Clinical significance of different bacterial load of Mycoplasma pneumoniae in patients with Mycoplasma pneumoniae pneumonia(J)Brazilian Journal of Infectious Diseases . 2013
  • 9Yun-Ju Ma,Shih-Min Wang,Yu-Hao Cho,Ching-Fen Shen,Ching-Chuan Liu,Hsin Chi,Yi-Chuan Huang,Li-Min Huang,Yhu-Chering Huang,Hsiao-Chuan Lin,Yu-Huai Ho,Jung-Jung Mu.??Clinical and epidemiological characteristics in children with community-acquired mycoplasma pneumonia in Taiwan: A nationwide surveillance(J)Journal of Microbiology, Immunology and Infection . 2014
  • 10F. M. Sánchez-Vargas,O. G. Gómez-Duarte.Mycoplasma pneumoniae—an emerging extra-pulmonary pathogen. Clinical Microbiology & Infection . 2008

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