摘要
目的:研究七氟醚全凭吸入麻醉对妇科腹腔镜手术患者血流动力学的影响。方法:抽取我院妇科于2011年9月至2013年9月期间行腹腔镜手术患者64例作为研究对象,对患者的病历资料作回顾性分析。结果:观察组患者的呼吸频率(RR)、血氧饱和度(SpO2)、二氧化碳分压(PE TCO2)分别为(19.62±2.06)min、(93.56±2.84)、(42.11±3.83)mmHg,对照组患者的RR、SpO2、PE TCO2分别为(25.62±2.49)min、(101.32±3.05)、(48.62±3.67)mmHg,差异具有统计学意义(P<0.05)。麻醉诱导前两组去甲肾上腺素(NE)、肾上腺素(E)、血浆皮质醇(cort)、血管紧张素Ⅱ(ATⅡ)无显著差异(P>0.05),观察组插管即刻NE[(0.43±0.01)ng/mL]、E[(0.15±0.02)ng/mL]、cort[(336±20)ng/mL]、ATⅡ[(63±4)ng/mL]与插管后NE[(0.42±0.02)ng/mL]、E[(0.16±0.01)ng/mL]、cort[(331±16)ng/mL]、ATⅡ[(60±8)ng/mL],各项水平均明显提升,对照组插管即刻NE[(0.58±0.05)ng/mL]、E[(0.32±0.02)ng/mL]、cort[(375±28)ng/mL]、ATⅡ[(63±5)ng/mL]与插管后NE[(0.65±0.03)ng/mL]、E[(0.33±0.02)ng/mL]、cort[(365±22)ng/mL]、ATⅡ[(62±5)ng/mL],各项水平均明显提升,且观察组上升水平相对较少(P<0.05)。结论:妇科患者行腹腔镜手术治疗期间,行七氟醚全凭吸入麻醉,可降低对血流动力学的影响,提高临床治疗安全性,
Objective： To study the effect of sevoflurane inhalation on hemodynamic indexes of patients with gynecological laparoscopic surgery. Methods： Clinical data of 64 patients with laparoscopic surgery admitted from September 2011 to September 2013 were retrospectively analyzed. Results, RR, SpO2 , 56 PETCO2 of observation group were （19.62±2.06） rain, （93.56±2.84）,（42.11±3.83） mmHg, respectively, and they were （25.62±2.49） min, （101.32±3.05） and （48.62±3.67）mmHg in control group, with significant difference between two groups （P〈 0.05）. There was no significant difference in NE, E, cort, or AT Ⅱ between two groups before anesthesia （P〉 0.05）. In observation group NE during intubation was （0.43±0.01） ng/mL, Ewas （0.15±0.02） ng/mL, cortwas （336±20） ng/mL, AT Ⅱwas （63±4） ng/mL; whileNE afterintubationwas （0.42 ± 0.02） ng/mL, E was （0.16±0.01） ng/mL, cort was （331±16） ng/mL, AT Ⅱ was （60±8） ng/mL. All indexes were significantly increased. While in the control group （0.58±0.05） NE during intubation was（0.58± 0.05）ng/mL, E was （0.32±0.02） ng/mL, cort was （375±28） ng/mL, AT Ⅱ was （63 ± 5） ng/mL and NE after intuba- tion was （0.65 ± 0.03） ng/mL, E was （0.33 ± 0.02） ng/mL, cort was （365±22） ng/mL, and AT Ⅱ was （62!5） ng/mL. All indexes were also significantly increased, but not as significant as that of observation group. Conclusion： During gynecologic laparoscopic surgery, sevoflurane inhalation can reduce the influence on hemodynamics, and improve the safety of treat- ment.
出处
《海南医学院学报》
CAS
2014年第12期1675-1677,共3页
Journal of Hainan Medical University
基金
湖北省科技计划项目(2009B030801316)~~
