摘要
目的:研究冠心病(coronary heart disease,CHD)患者心外膜脂肪组织(epicardial adipose tissue,EAT)的超声心动图表现,分析其对冠心病的诊断价值。方法:选取2012年12月至2013年4月期间于青岛大学附属医院心内科住院的CHD患者53例作为CHD组,选取同期体检中心健康人员40例作为正常组,所有受试者均接受超声EAT测量和冠状动脉造影检查,统计所有患者超声测量的右心室前壁舒张末期、收缩末期EAT厚度,应用ROC曲线分析法分析其对CHD的诊断价值。结果:CHD组患者右心室前壁舒张、收缩末期EAT厚度明显高于正常组,差异有统计学意义(P<0.05);CHD组患者右心室前壁收缩末期心外膜脂肪组织增厚程度明显高于舒张末期,差异有统计学意义(P<0.05);以EAT厚度>4.5mm诊断CHD,在舒张末期时,敏感度为93.26%,特异度为73.21%,ROC曲线下面积为0.736,在收缩末期时,敏感度为96.53%,特异度为79.49%,ROC曲线下面积为0.872。结论:CHD患者右心室前壁舒张、收缩末期EAT明显增厚,收缩末期EAT增厚程度更为显著,超声测量收缩末期EAT厚度可作为检查冠心病新的诊断指标。
Objective： To study the echocardiographic features of epicardial adipose tissue （EAT） in patients with coronary heart disease（CHD） and analysis the diagnostic value for CHD. Methods：There were total 93 patients,53 of CHD group and 40 of normal control （NC） group. All patients were evaluated by transthoracic echocardiography with measurement of EAT thickness in the anterior wall of right ventricle of heart both at end-systole and end-diastole phase. Results：EAT thickness was significantly different between CHD group and NC group（P〈0.05）.EAT thickness of the anterior wall of right ventricle increased more at end-systole than that at end- diastole phase（P〈0.05）.EAT thickness〉4.5mm showed 93.26% sensitivity and 73.21% specificity. ROC area 0.736, at end-diastole phase. The same cut-off value showed 96.53% sensitivity and 79.49% specificity, ROC area 0.872, at end-systole phase. Conclusion： EAT thickness of the anterior wall of right ventricle measured by transthoracic echocardiography at end-systole phase may serve as a new diagnostic diameter for coronary heart disease.
出处
《中国医药导刊》
2015年第1期3-4,6,共3页
Chinese Journal of Medicinal Guide
基金
国家自然科学基金资助项目(编号:81072237)
课题名称:超声测量冠心病心外膜脂肪组织的临床研究
关键词
超声心动图
心外膜脂肪组织
冠心病
Echocardiography
Epicardial adipose tissue
Coronary heart disease
