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长链非编码RNA与胃癌诊断 预后及耐药性研究进展 被引量:2

Research progress in lnc RNAs and the diagnosis, prognosis, and drug resistance of gastric cancer
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摘要 长链非编码RNA(long non-coding RNA,lnc RNA)是一组长度超过200bp的非编码RNA。其缺少完整蛋白编码功能,具有调控基因表达作用。近年来研究发现,lnc RNA与胃癌的诊断、预后及耐药性密切相关。本文结合国内外最新报道,对ln-c RNA在胃癌的诊断,预后及耐药性方面的研究进展做一综述。 Long non-coding RNAs (lncRNAs) are noncoding RNAs with lengths exceeding 200 bp. These lncRNAs cannot code complete proteins but control gene expression. Recent studies have shown that lncRNAs are closely related to the diagnosis, prognosis, and drug resistance of gastric cancer. This article summarizes the recent progress of studies in China and abroad on lncRNAs relative to the diagnosis, prognosis, and drug resistance of gastric cancer.
出处 《中国肿瘤临床》 CAS CSCD 北大核心 2015年第1期71-76,共6页 Chinese Journal of Clinical Oncology
基金 国家自然科学基金项目(编号:81272601) 江苏省科技厅临床医学科技专项基金项目(编号:BL2014096) 江苏省医学重点人才基金项目(编号:RC2011080)资助~~
关键词 长链非编码RNA 胃癌 诊断 预后 耐药性 long non-coding RNA, gastric cancer, diagnosis, prognosis, drug resistance
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