期刊文献+

缺铁性贫血诊断的研究进展 被引量:13

Research Progress on the Diagnosis of Iron Deficiency Anemia
在线阅读 下载PDF
导出
摘要 缺铁性贫血(IDA)是体内贮存铁缺乏,影响血红素合成引起的贫血。IDA为最常见的贫血,目前临床上主要以外周血常规参数、铁代谢参数作为诊断指标,但以上指标敏感性差,易受其他因素的影响,给IDA的诊断带来一定困难。目前,IDA的诊断在某些领域取得了新的研究进展,如通过对铁调素、网织红细胞血红蛋白含量、低血红蛋白浓度的检测,给IDA带来了具有敏感性高、方便、有效的诊断方法,值得临床医师注意。 Iron deficiency anemia( IDA) refers to the anemia caused by the iron deficiency in the body storage,which affects heme synthesis. IDA is one of the most common kind of anemia,currently,peripheral blood routine parameters,iron metabolism parameters are mainly used as diagnostic indexes of IDA,however,those indexes have poor sensitivity,and are easily affected by other factors,that brings difficulties to the diagnosis of IDA. At present,new research progress has been made in some areas of IDA diagnosis,such as the detection of hepcidin,reticulocyte hemoglobin content,low hemoglobin density,etc. Such detections have brought more convenient and effective methods with high sensitivity to the diagnosis of IDA,and are worth to be paid more attention by clinicians.
作者 李浩 付美兰
出处 《医学综述》 2015年第3期462-464,共3页 Medical Recapitulate
关键词 缺铁性贫血 铁调素 网织红细胞血红蛋白 低血红蛋白浓度 Iron deficiency anemia Hepcidin Reticulocyte hemoglobin Low haemoglobin density
  • 相关文献

参考文献22

  • 1杨一芬,郭怡华.网织红细胞血红蛋白含量在缺铁性贫血诊断中的应用价值[J].实用预防医学,2010,17(12):2497-2499. 被引量:12
  • 2江虹,徐灿,吕瑞雪,郭曼英,曾素根,左永太.网织红细胞血红蛋白含量在缺铁性贫血的诊断和鉴别诊断中的应用[J].实用医学杂志,2010,26(12):2136-2138. 被引量:39
  • 3Bergamaschi G,Villani L.Serum hepcidin:a novel diagnostic tool in disorders of iron metaboiism[J].Haematologica,2009,94(12):1631-1633.
  • 4Ravasi G,Pelucchi S,Trombini P,et al.Hepcidin expression in iron overload diseases is variably modulated by circulating cactors[J].PLo S One,2012,7(5):e36425.
  • 5Chung B,Chaston T.Hepcidin decreases iron transporter expression in vivo in mouse duodenum and spleen and in vitro in THP-1macrophages and intestinal Caco-2 cells[J].JNutr,2009,139(8):1457-1462.
  • 6Anderson GJ,Frazer DM.Recent advances in intestinal iron transport[J].Curr Gastroenterol Rep,2005,7(5):365-372.
  • 7Sun CC,Vaja V,Babitt JL,et al.Targeting the hepcidin-ferroportin axis to develop newtreatment strategies for anemia of chronic disease and anemiaof inflammation[J].Am J Hematol,2012,87(4):392-400.
  • 8赵晋英,周沛,刘翠,曾漂,岳云,谢奔,胡晓娇,黄泽智,李艳伟.血清铁调素含量在鉴别缺铁性贫血和慢性病贫血中的意义[J].广东医学,2010,31(23):3091-3093. 被引量:17
  • 9Finberg KE.Unraveling mechanisms regulating systemic iron homeostasis[J].Hematology Am Soc Hematol Educ Program,2011,2011:532-537.
  • 10Elizabeta N,Tomas G.The role of hepcidin in iron metabolism[J].Acta Haematol,2009,122(2/3):78-86.

二级参考文献43

共引文献67

同被引文献82

引证文献13

二级引证文献89

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部