摘要
[目的]观察大黄通便颗粒对急性胰腺炎的临床疗效。[方法]共计44例急性胰腺炎患者纳入研究,随机分为2组:对照组18例、干预组26例。所有患者均接受常规治疗。干预组在常规治疗的基础上加用大黄通便颗粒。记录2组总住院天数、腹痛缓解时间与首次排便时间。检测患者治疗前后的血尿淀粉酶及血清炎性因子。[结果]对照组总有效率83.3%,干预组总有效率88.5%,2组差异无统计学意义,但后者显效率更高。相比对照组,干预组患者的总住院天数、腹痛缓解时间与首次排便时间均明显缩短(P<0.05)。治疗后,2组患者血尿淀粉酶及血清炎性因子都显著下降(P<0.01),但干预组更为明显。[结论]大黄通便颗粒可以增加治疗后的显效率,减少住院天数,缓解疼痛、促进排便及降低血尿淀粉酶和体内炎症反应。
[Objective]To observe the clinical efficacy of Dahuang Tongbian Granules（DTG）on acute pancreatitis（AP）.[Methods]Forty-four AP patients were enrolled in this study and were randomly divided into 2groups：conventional treatment group（n=18）and DTG treatment group（n=26）.All patients received the conventional treatments.In addition,DTG treatment group received Dahuang Tongbian granules.The bellyache relief time,total hospital stay and first defecation time were recorded.The levels of amylase（in serum and urine）and serum inflammatory factors were measured before and after the treatment.[Results]The total efficiency of conventional treatment group and DTG treatment group were 83.3% and88.5%respectively（P〉0.05）,while the marked effective rate in the latter was higher（P〈0.05）.Compared to the conventional treatment group,DTG treatment group showed less bellyache relief time,total hospital stay and first defecation time.After the treatment,both groups showed lower levels of amylase（in serum and urine）and serum inflammatory factors（P〈0.01）,especially in DTG treatment group.[Conclusion]Dahuang Tongbian Granules had good effect for acute pancreatitis by significantly increasing marked effective rate,shortening the hospital stay,relieving pain,promoting defecation and reducing the amylase levels and inflammatory response.
出处
《中国中西医结合消化杂志》
CAS
2015年第2期125-127,共3页
Chinese Journal of Integrated Traditional and Western Medicine on Digestion
关键词
大黄通便颗粒
急性胰腺炎
腹痛
淀粉酶
炎症
Dahuang Tongbian Granules
acute pancreatitis
bellyache
amylase
inflammation
