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A substrate scaffold for assessment of nerve regeneration and neurodegenerative diseases

A substrate scaffold for assessment of nerve regeneration and neurodegenerative diseases
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摘要 Neuroregenerafion is a complex topic in neurosci- ence and includes 3 concepts: neurogenesis, neuro- plasticity, and neurorestoration. After injury of the nervous system, axons have the capacity for self-re- pair, regrowth or proliferation. The peripheral ner- vous system is more effective at restoring damaged axons than the central nervous system (CNS). This is because formation of scar tissue in the CNS in- fluences neural regrowth or synthesis of growth-in- hibiting proteins, thereby preventing reconstruction of a neural circuit (Silver and Miller, 2004; Enciu et al., 2011). Parkinson's disease (PD) and Alzheimer's disease (AD) are two most common degenerative diseases of the CNS among the elderly. Neuroregenerafion is a complex topic in neurosci- ence and includes 3 concepts: neurogenesis, neuro- plasticity, and neurorestoration. After injury of the nervous system, axons have the capacity for self-re- pair, regrowth or proliferation. The peripheral ner- vous system is more effective at restoring damaged axons than the central nervous system (CNS). This is because formation of scar tissue in the CNS in- fluences neural regrowth or synthesis of growth-in- hibiting proteins, thereby preventing reconstruction of a neural circuit (Silver and Miller, 2004; Enciu et al., 2011). Parkinson's disease (PD) and Alzheimer's disease (AD) are two most common degenerative diseases of the CNS among the elderly.
出处 《Neural Regeneration Research》 SCIE CAS CSCD 2015年第1期41-42,共2页 中国神经再生研究(英文版)
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