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醒脑开窍针刺法结合高压氧治疗一氧化碳中毒迟发性脑病的临床观察 被引量:25

Clinical observation on delayed encephalopathy after carbon monoxide poisoning treated with acupuncture to restore consciousness combined with hyperbaric oxygen treatment
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摘要 目的:比较醒脑开窍针刺法结合高压氧与单纯高压氧治疗一氧化碳中毒迟发性脑病(DEACMP)的疗效差异。方法:将41例DEACMP患者随机分为观察组(21例)和对照组(20例)。观察组针刺内关、水沟、百会、四神聪、风池、合谷、三阴交、太冲,配合高压氧治疗;对照组仅予高压氧治疗。均每日1次,连续治疗5天为一疗程,疗程间隔2天,两组均治疗6个疗程。比较两组治疗前后简易智能精神状态检查量表(MMSE)评分、日常生活能力Barthel指数(BI)评分、常规脑电图(EEG)变化情况。结果:两组治疗后MMSE评分、BI评分、EEG异常程度均较治疗前明显改善(均P<0.01);观察组治疗后MMSE评分、BI评分较对照组提高更明显(均P<0.05);观察组治疗后EEG异常程度改善情况亦优于对照组(P<0.05)。结论:醒脑开窍针刺法结合高压氧能明显改善DEACMP患者认知功能、日常生活能力及脑电图异常,优于单纯高压氧治疗。 Objective To compare the efficacy differences on delayed encephalopathy after carbon monoxide poisoning (DEA(2MP) between acupuncture to restore consciousness combined with hyperbaric oxygen treatment and simple hyperbaric oxygen treatment. Methods Forty-one patients with DEACMP were randomly divided into an observation group (21 cases) and a control group (20 eases). In the observation group, acupuncture was ap- plied at Neiguan (PC 6). Shuigou (GV 26), Baihui (GV 20), Sishencong (EX-HN 1), Fengchi (GB 20), Hegu (LI 4). Sanyinjiao (SP 6) and Taichong (LR 3,), and hyperbaric oxygen treatment was given as well. In the con- trol group, simple hyperbaric oxygen treatment was used. The treatment was adopted once every day, and conti- nuous 5 days' treatment made one session in the two groups. There were two days at the interval between twoses- sions and 6 sessions in the two groups. The changes of scores of mini mental state examination (MMSE) and Bar- thel index (BI) for activity of daily life and routine electroencephalogram (EEG) before and after treatment were compared. Results After treatment, the scores of MMSE and BI and EEG were all improved compared with those before treatment (all P〈0.01 ). The raise of the scores of MMSE and BI in the observation group was more ob- vious than that in the control group (both P〈0.05) and the improvement of EEG abnormal condition in the obser- vation group was also superior to that in the control group after treatment (P〈0.05). Conclusion Acupuncture to restore consciousness combined with hyperbaric oxygen could obviously improve the cognitive function, activity of daily life and changes of EEG, and it is better than simple hyperbaric oxygen treatment.
出处 《中国针灸》 CAS CSCD 北大核心 2015年第3期213-216,共4页 Chinese Acupuncture & Moxibustion
关键词 一氧化碳中毒 迟发性脑病 醒脑开窍针刺法 高压氧 随机对照研究 earbon monoxide poisoning delayed encephalopathy acupuncture to restore consciousness hyperbaric oxygen lreatment randomized controlled trial (RCT)
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