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维生素D与妊娠期糖尿病 被引量:20

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摘要 妊娠期糖尿病(gestational diabetes mellitus,GDM)指妊娠期发生的不同程度的糖代谢异常[1].国内外关于GDM的诊断标准一直存在争议.2014年8月,中华医学会妇产科分会产科学组和中华医学会围产医学分会妊娠合并糖尿病协作组发表了《妊娠合并糖尿病诊治指南(2014)》[1],以指导临床实践.尽管诊断标准不尽相同,全球流行病学调查均显示GDM的发病率正不断攀升.我国13家医院2010年1月至2012年2月的调查数据显示,我国GDM的患病率为17.5%[2].近年来维生素D与GDM的关系引起了广泛关注.动物研究提示,维生素D可促进胰腺外分泌作用,并可改善胰岛素抵抗.也有临床研究提示,维生素D缺乏与β细胞功能不良有关[3].维生素D可以从食物中获取,容易补充.如果证实维生素D可以预防或改善GDM患者的妊娠结局,则可通过补充维生素D对高危孕妇进行干预[4].
作者 王薇 杨慧霞
出处 《中华围产医学杂志》 CAS CSCD 2015年第2期140-144,共5页 Chinese Journal of Perinatal Medicine
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共引文献372

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