摘要
【目的】观察加味赤石脂禹余粮汤联合热敏灸对肝硬化腹水并顽固性腹泻的临床疗效。【方法】选择肝硬化腹水并顽固性腹泻患者60例,随机分为治疗组与对照组各30例,对照组采用西医常规疗法加中药加味赤石脂禹余粮汤治疗,治疗组在对照组治疗基础上加用热敏灸疗法,观察2组患者腹泻、腹水及肝功能指标[总胆红素(TBIL)、丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)、白蛋白(ALB)、前白蛋白(PA)]改善情况。【结果】(1)腹泻疗效:治疗组总有效率为100.00%,优于对照组的86.67%(P<0.05)。(2)腹水疗效:经彩超检查,治疗后2组的肝硬化腹水均有显著改善(P<0.05),且治疗组疗效优于对照组(P<0.05)。(3)肝功能作用:治疗后,2组TBIL、ALT、AST、ALB、PA指标均显著改善(P<0.05),且治疗组的改善作用均优于对照组(P<0.05)。(4)不良反应及随访情况:治疗过程中,治疗组与对照组均未发生明显不良反应。3个月后随访,对照组腹泻治愈患者中复发5例,治疗组无复发病例。【结论】加味赤石脂禹余粮汤联合热敏灸对肝硬化腹水并顽固性腹泻患者疗效显著,具有止泻迅速、应用方便、安全可靠等优点,并且有加速腹水消退、促进肝功能恢复的作用。
Objective To observe the therapeutic effect of modified Chishizhi Yuyuliang Decoction plus heat-sensitive acupoint moxibustion for the treatment of liver cirrhosis induced ascites complicated with refractory diarrhea. Methods Sixty liver cirrhosis induced ascites patients complicated with refractory diarrhea were evenly randomized into treatment group and control group. Both groups were given conventional western medicine combined with modified Chishizhi Yuyuliang Decoction, and additionally, the treatment group was given heatsensitive acupoint moxibustion. The outcomes included relief of diarrhea and ascites as well as hepatic function indexes of total bilirubin（TBIL）, alanine aminotransferase（ALT）, aspartic transaminase（AST）, albumin（ALB）, and prealbumin（PA）. Results（1） The total effective rate of diarrhea was 100.00% in the treatment group and was 86.67% in the control group, the difference being significant（ P〈0.05）.（ 2） The results of color ultrasound showed that the ascites was much relieved in both groups after treatment（ P〈0.05 compared with that before treatment）, and the relief in the treatment group was superior to that in the control group（P〈0.05）.（ 3） After treatment, the hepatic function indexes of TBIL, ALT, AST, ALB and PA were much improved in both groups（ P〈0.05）, and the improvement in the treatment group was superior to that in the control group（P〈0.05）.（4） During the treatment, no obvious adverse reaction was found in both groups. The results of follow-up after 3 months showed that 5 cases of the control group had diarrhea recurrence while no case of diarrhea recurrence was found in the treatment group. Conclusion Modified Chishizhi Yuyuliang Decoction plus heat-sensitive acupoint moxibustion exerts obvious effect for the treatment of liver cirrhosis induced ascites complicated with refractory diarrhea, showing advantages of stopping diarrhea rapidly, being practical and safe, promoting the subsidence of ascites, and promoting hepatic function recovery.
出处
《广州中医药大学学报》
CAS
2015年第2期255-258,共4页
Journal of Guangzhou University of Traditional Chinese Medicine
基金
河南省科技厅科技攻关项目(编号:132102310154)
关键词
肝硬化腹水/中西医结合疗法
腹泻/中西医结合疗法
加味赤石脂禹余粮汤/治疗应用
热敏灸
Liver cirrhosis induced ascites / TCM-WM therapy
Modified Diarrhea / TCM-WM therapy
Modified Chishizhi Yuyuliang Decoction / therapeutic use
Heat-sensitive acupoint moxibustion
