摘要
目的观察醒脑静注射液治疗急性脑出血的临床疗效。方法选取我院2012-01—2014-01收治的急性脑出血患者65例,随机分为2组,均给予脱水降颅压、神经营养及康复等治疗措施,对照组32例,在常规治疗的基础上加用胞二磷胆碱钠注射液入5%葡萄糖注射液250mL中静滴,1次/d;试验组33例在常规治疗的基础上加用20mL醒脑静注射液加入250mL 0.9%氯化钠注射液中静滴,1次/d。2组均治疗14d为一个疗程。观察2组患者治疗前后美国国立卫生研究院卒中量表(NIHSS)评分及日常生活活动能力评分(ADL),检测治疗前后血清超敏C反应蛋白(hs-CRP)的水平,对比2组临床疗效。结果治疗14d后,试验组患者血清hs-CRP水平较对照组下降更为显著,差异有统计学意义(P<0.05);2组治疗后NIHSS评分及ADL评分均有所改善,但试验组改善更为明显(P<0.05);试验组总有效率明显高于对照组,2组比较差异有统计学意义(P<0.05)。结论醒脑静注射液治疗急性脑出血患者效果明显,可有效改善患者神经功能,提高日常生活活动能力,降低血清hs-CRP水平,且安全性较高,值得临床推广。
Objective To observe clinical efficacy of Xingnaojing injection in treating acute cerebral hemorrhage.Methods Sixty-five patients with acute cerebral hemorrhage admitted to the hospital from January 2012 were selected,and were randomly divided into two groups,patients in both groups were subject to intracranial dehydration pressure reduction,neurotrophy and rehabilitation treatment measures,32 patient in the control group were subject to intravenous drip（once per day）with citicoline sodium injection mixed into 250mL of 5% glucose injection on the basis of conventional treatment,and 33 patients in the experiment group were subject to intravenous drip（once per day）with 20mL of Xingnaojing injection mixed into 250mL of 0.9% sodium chloride.The treatment cycle for patients in both groups hit two weeks.National Institute of health Stroke Scale（NIHSS）score and activities of daily life（ADL）score of patients before and after treatment were observed,the level of serum high sensitivity C-reactive protein（hs-CRP）was detected,and clinical efficacy on patients in two groups was compared.Results The serum hs-CRP level of patients in the experimental group decreased more significantly when compared to that of patients in the control group,the difference was statistically significant（P〈0.05）;NIHSS score and ADL score of patients in 2 groups after treatment were improved,but such scores of patients in the experimental group were more significantly improved（P〈0.05）.The total effective rate of patients in the experimental group was significantly higher than that of patients in the control group,and the comparative difference of patients in two groups was statistically significant（P〈0.05）.Conclusion Xingnaojing injection delivers significant efficacy in treating patients with acute cerebral hemorrhage,and it can effectively improve nerve function,activities of daily living and level of reduce serum hs-CRP with high security,being worthy of clinical promotion.
出处
《中国实用神经疾病杂志》
2015年第4期15-16,共2页
Chinese Journal of Practical Nervous Diseases
关键词
急性脑出血
醒脑静注射液
胞二磷胆碱钠注射液
Acute cerebral hemorrhage
Xingnaojing injection
Citicoline sodium injection
