摘要
目的探讨核磁共振弥散张量成像诊断轻度脊髓型颈椎病的临床价值。方法入选我院2012年6月至2014年6月收治的轻度脊髓型颈椎病患者62例(按照颈髓磁共振平扫结果分为A组和B组:A组32例,颈髓信号正常,颈髓60个节段受压;B组30例,颈髓信号正常,硬膜囊63个节段受压),同时入选30例体检健康者(C组)进行90个颈髓节段磁共振检查,评估各组的分数各向异性值(FA)及表观扩散系数(ADC),评估平行于颈椎的长径、前后径、左右径的本征值E1、E2、E3,计算出平均弥散系数MD值、横向平均弥散系数E⊥值:MD=(E1+E2+E3)/3;E⊥=(E2+E3)/2。结果健康对照组不同脊髓节段FA值及ADC值之间差异无统计学意义(P>0.05);A组的脊髓节段平均ADC值显著高于C组,差异具有统计学意义(P<0.05);A组的脊髓节段FA平均值显著低于C组,差异具有统计学意义(P<0.05);B组的脊髓节段平均ADC值显著高于C组,差异具有统计学意义(P<0.05);B组的脊髓节段FA平均值显著低于C组,差异具有统计学意义(P<0.05);两组的E1值比较差异无统计学意义(P>0.05),病变组的E2、E3、MD值、E⊥值指标显著低于健康组,差异具有统计学意义(P<0.05)。结论轻度脊髓型颈椎病进行磁共振张量成像检查,可准确早期量化该病的颈髓微结构变化,对早期诊断发现轻度脊髓型颈椎病诊断具有重要的临床意义。
Objective to investigate the magnetic resonance diffusion tensor imaging in the diagnosis of mild myelopathic type. Methods in our hospital in 2012.6-2014.6 were 62 cases of mild spondylotic myelopathy （according to the cervical spinal mri scan results are divided into group A and group B, group A 32 cases, normal cervical spinal signal, compression of cervical spinal 60 segment; group B, 30 cases （group C）normal cervical spinal signal, compression of dural sac 63 section）, and 30 healthy subjects were selected 90 cervical spinal segment mri examination, evaluation of each value fractional anisotropy （FA） and apparent diffusion coefficient （ADC）.Evaluation parallel to the length to diameter of the cervical spine, before and after about diameter, the diameter of the eigenvalue E1, E2 and E3, calculate the average dispersion coefficient value, average transverse dispersion coefficient E⊥an MD, MD=（E1＋E2＋E3）/3;E⊥=coming （E2 and E3）/2. Results healthy controls different spinal cord segment between the FA and ADC values differences had no statistical significance （P〉0.05）;Spinal cord segmental average ADC values of group A is significantly higher than in group C, statistically significant difference （P〈0.05）;Group A spinal cord segmental FA average significantly lower than that of group C, statistically significant difference （P〈0.05）;Group B of the spinal cord segmental average ADC values significantly higher than that of group C, statistically significant difference （P〈0.05）;Group B of the spinal cord segmental FA average significantly lower than that of group C, statistically significant difference （P〈0.05）. Conclusion mild magnetic resonance tensor imaging myelopathic type cervical vertebra disease, can accurately quantify the cervical spinal microstructure changes of the disease, early mild myelopathic type cervical vertebra disease diagnosis of early diagnosis findings have important clinical significance.
出处
《中国CT和MRI杂志》
2015年第3期16-18,共3页
Chinese Journal of CT and MRI
关键词
表观扩散系数
分数各向异性值
弥散张量成像技术
The Apparent Diffusion Coefficient
Scores of Anisotropic Value
Diffusion Tensor Imaging
