摘要
目的探讨研究银屑病与代谢综合征的相关性,为银屑病的合理诊治提供指导。方法选取符合标准的100例银屑病患者作为观察组,选择同期诊治的100例无免疫系统疾病的带状疱疹患者作为对照组。比较观察组与对照组患者中代谢综合征的发病率;比较观察组患者中寻常型与重型银屑病患者各项指标的差异;对银屑病合并代谢综合征的危险因素的Logistic回归分析。结果观察组患者MS总患病率为38.0%,显著性高于对照组的20.0%。观察组患者中男性MS患者与女性MS患者分别为32.6%与42.6%,显著性高于对照组的16.3%与22.8%(P<0.05)。寻常型银屑病患者的FPG与TG分别为(5.58±1.52)mmol/L与(1.56±0.30)mmol/L,均显著性低于重型银屑病的(6.51±1.09)mmol/L与(1.76±0.22)mmol/L(P<0.05)。危险因素的Logistic回归分析表明,年龄、A型性格、不吃早餐与酗酒是银屑病合并代谢综合征发病的独立危险因素。结论银屑病与代谢综合征有着密切的相关性。银屑病患者应当积极调整心态,调整生活习惯,积极配合治疗,降低银屑病患者代谢综合征的发生率。
Objective To investigate the correlation between psoriasis and metabolic syndrome（MS） in order to guide reasonable diagnosis and treatment of psoriasis. Methods 100 patients of psoriasis were chosen for observed group, while 100 patients of herpes zoster were chosen for control group at the same time. The incidence of metabolic syndrome between the two groups were compared. The difference in indicators between common type psoriasis and severe psoriasis were compared. The Logistic regression analysis was used for the risk factors. Results The total MS prevalence in observed group was 38.0%, which was significantly higher than that of the control group which was 20.0% （P 〈 0.05）. The MS prevalence of male and female in observed group were 32.6% and 42.6%, which were significantly higher than that of the control group which were 16.3% and 22.8% （P 〈 0.05）. The FPG and TG in common type psoriasis were （5.58±1.52）mmol/L and （1.56±0.30）mmol/L, which were significantly lower than that in severe type psoriasis which were （6.51±1.09）mmol/L and （1.76±0.22）mmol/L （P〈0.05）. The Logistic regression analysis of risk factors showed that age, type A personality, no breakfast and alcoholism were independent risk factors. Conclusion Psoriasis has close correlation with MS. Psoriasis patients should actively adjust mentality, living habits and cooperate with treatment in order to reduce the incidence of MS.
出处
《中国医药科学》
2015年第3期9-11,17,共4页
China Medicine And Pharmacy
基金
广东省肇庆市科技创新计划项目(2014E189)
关键词
银屑病
代谢综合征
危险因素
相关性
Psoriasis
Metabolic syndrome
Risk factors
Correlation
