摘要
检测了35例囊尾蚴病患者和30例献血员血清中总IgE水平、特异性IgE和组织胺含量,并进行了间接特异性肥大细胞脱颗粒试验。患者血清中总IgE水平达730.6IU/ml,而正常人的总IgE水平仅为186.5IU/ml。患者血清中特异性IgE的阳性率为85.7％,间接特异性肥大细胞脱颗粒的阳性率和血清中组织胺含量均明显高于正常人。
Total IgE, specific IgE and histamine in sera from 35 documented cases of cysticercosis and 30 transfusion donors were measured and mast cell degranulation test was perforired. Total IgE levels (730.6IU/ml), the positive rate of specific IgE (85.7%), histamine levels (5.3μg/ml) and the positive rate of mast cell degranulation (42.9%) of the patients were found to be significantly higher than those of the normal group (P<0.01).The results suggested that the antigen of Cysticercus cellulosae could induce IgE production and mast cell degranulation, resulting in the release of histamine. It was, therefore, deemed that the IgE and IgE-mediated immunoreaction might be involved in the pathogenesis of human cysticercosis.
出处
《中国寄生虫学与寄生虫病杂志》
CAS
CSCD
北大核心
1991年第1期68-70,共3页
Chinese Journal of Parasitology and Parasitic Diseases
