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多发性硬化患者血清尿酸水平 被引量:3

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摘要 多发性硬化( MS)是一种免疫介导的中枢神经系统脱髓鞘疾病,病变晚期轴索亦可受到破坏,其病因和发病机制尚不十分明确,复发率及致残率高。尿酸( UA)是嘌呤核苷酸代谢的终产物,是内源性的抗氧化剂和过氧化亚硝酸阴离子的天然清除剂。临床研究证实MS患者血清UA水平较低,同时给予UA治疗可抑制其病情发展〔1〕。本文探讨血清UA水平在MS发病中的作用机制。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2014年第22期6500-6501,共2页 Chinese Journal of Gerontology
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