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正交设计优选橘红痰咳颗粒提取工艺的研究

Study on the Optimization of the Extract Technology of Juhong Tanke Granuces by Orthogonal Design Method
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摘要 目的优选橘红痰咳颗粒水提取最佳工艺。方法采用正交设计L9(34),以HPLC法测定提取物中柚皮苷的含量,并进行方差分析。结果优选橘红痰咳颗粒水提取最佳工艺参数为A1B3C2D1,即加水量为10倍,提取次数为2次,提取时间为每次1 h,浸泡时间为60 min。结论验证实验显示,优选的提取工艺参数合理有据,可推广应用于橘红痰咳颗粒的提取工艺。 Objective: To optimize the extract technology of Juhong tanke granuces. Methods: An orthogonal design was applied. The extractive rate of naringinin determined by HPLC was used as the marker of detection.Results: The optimum technology of Juhong Tanke granuces was A1B3C2D1, that is, the medicinal materials was soaked for 60 min with10 folds amount of water and boiled two times, 2 hours for each time for the first time. For the second time the medicinal materials was 8 folds amount of water, 1 hours each time. Conclusion: This method can be used for the extract technology of Juhong tanke granuces.
出处 《襄阳职业技术学院学报》 2015年第2期31-34,共4页 Journal of Xiangyang Polytechnic
关键词 橘红痰咳颗粒 HPLC法 正交设计 提取工艺 Juhong tanke granuces Orthogonal design method Extract technology Naringinin
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