摘要
探讨丙型肝炎患者体内HCV-RNA、HCV-Ab、ALT和TP间的相互关系。采用ELISA检测708例HCV-Ab阳性的丙型肝炎疑似患者,以RT-PCR检测血清HCV-RNA载量,全自动生化仪定量检测ALT和TP。HCV-Ab表达水平与HCV-RNA载量有关,HCVRNA载量与ALT异常率呈正相关性,但HCV-RNA载量与ALT含量无相关性,与TP含量亦无相关性。708例HCV-Ab阳性患者中男性多于女性,差异无统计学意义(P>0.05);40岁以上患者比例多于40岁以下患者比例,差异有统计学意义(P<0.05)。HCV-RNA与HCV-Ab、ALT具有一定相关性,丙型肝炎以40岁以上男性患者多见,应引起临床重视。
In order to investigate the relativity among HCV- RNA,HCV- Ab,ALT and TP in hepatitis C patients,708 suspected hepatitis C patients with HCV- Ab positive were checked by using the ELISA method,with real- time detecting HCV- RNA in those bloods by Fluorescentrt- PCR,ALT and TP detected by automatic biochemical analyzer. The test results showed that HCV- Ab expression level is related with HCV- RNA content. HCV- RNA content is positively correlated with abnormal rate of ALT. But HCV- RNA content is not correlated with ALT content and TP content. Among the 708 patients,the HCV- Ab positive percentage of men is more than women,and there is no statistically significant difference（ P〉0.05）; the ratio of the ≥40 years old patients is greater than 40 years old patients,and the difference is statistically significant（ P〈0.05）. HCV-RNA,HCV- Ab and ALT have certain relativity. Among hepatitis C patients men of over 40 years old are more,and should be paid more clinical attention.
出处
《安徽理工大学学报（自然科学版）》
CAS
2015年第1期78-82,共5页
Journal of Anhui University of Science and Technology:Natural Science
