摘要
目的对毛樱桃(Cerasus tomentosa(Thunb.)Wall.)叶的化学成分进行研究。方法采用减压柱色谱、Sephadex LH-20、ODS柱色谱、硅胶柱色谱以及制备高效液相色谱等方法对毛樱桃叶的体积分数为70%的乙醇提取物进行提取分离,根据理化性质及波谱数据鉴定其结构。结果从毛樱桃叶的体积分数为70%的乙醇提取物中分离得到10个化合物,分别鉴定为(+)-丁香树脂醇[(+)-syringaresinol,1]、(+)-丁香树脂醇-4-O-β-D--吡喃葡萄糖苷[(+)-syringaresinol-4-O-β-Dglucopyranoside,2]、7S,8R-二氢去氢双松柏醇(7S,8R-dihydrodehydrodiconiferyl alcohol,3),7S,8R-5-甲氧基二氢去氢双松柏醇(7S,8R-5-methoxydihydrodehydrodiconiferyl alcohol,4)、山奈酚(kaempferol,5)、槲皮素(quercetin,6)、(-)-表儿茶素[(-)-epicatechin,7)、白蜡树精-6-β-D--半乳糖苷(fraxinol-6-β-D-galactopyranoside,8)、1-(4-羟基-3-甲氧基苯基)-2-[4-(3-羟丙基)-2-甲氧基苯氧基]丙烷-1,3-二醇{1-(4-hydroxy-3-methoxyphenyl)-2-[4-(3-hydroxypropyl)-2-methoxyphenoxy]propane-1,3-diol,9}、5,5'-二甲氧基-7-氧化落叶松脂醇(5,5'-dimethoxy-7-oxolariciresinol,10)。结论化合物2、4、10为从李属植物中首次分离得到,化合物1、3、8、9为从该植物中首次分离得到。
Objective To study the chemical constituents of the leaves of Cerasus tomentosa. Methods The chemical constituents of 70% （φ）ethanol extract of the leaves of Cerasus tomentosa were isolated by various chromatographic techniques including vacuum liquid chromatography, Sephadex LH-20, ODS chromatogra- phy column, silica gel column and p-HPLC, and the structures were identified with the help of physico- chemical characters and spectroscopic techniques. Results Ten compounds were isolated from 70% ethanol- water extraction and their structures were identified as （ ＋ ）-syringaresinol （1）, （ ＋ ）-syringaresinol-4-O-β- D-glucopyranoside （2）, 7S, 8R-dihydrodehydrodiconiferyl alcohol （ 3 ）, 7S, 8R-5-methoxydihydrodehydrodi- coniferyl alcohol（4）, kaempferol （5）, quercetin （6） （ - ） -epicatechin （ 7 ）, fraxinol-6-β-D-galactopyranoside （ 8 ）, 1 - （ 4-hydroxy-3-methoxyphenyl ） -2- [ 4- （ 3-hydroxypropyl ） -2-methoxyphenoxy ] propane-l, 3-diol （ 9 ） and 5,5 ＇-dimethoxy-7-oxolariciresinol （10）. Conclusions Compounds 2,4 and 10 are firstly isolated from Prunus genus. Compounds 1,3,8 and 9 are isolated from this plant for the first time.
出处
《沈阳药科大学学报》
CAS
CSCD
北大核心
2015年第4期256-260,共5页
Journal of Shenyang Pharmaceutical University
关键词
毛樱桃
化学成分
结构鉴定
Cerasus tomentosa
chemical constituents
structure identification
