摘要
目的研究小剂量间歇补铁法治疗小儿缺铁性贫血(IDA)的临床疗效及副作用。方法将133例缺铁性贫血患儿半随机分为间歇治疗组(A组)和常规治疗组(B组),分别给予小剂量间歇补铁及常规剂量每日补铁治疗,2个月后复查患儿的血清铁蛋白(SF)和血红蛋白(Hb),同时观察并记录患儿不良反应。结果治疗前两组比较SF和Hb基本相同,差异无统计学意义(P>0.05),治疗前后比较两组的SF及Hb均显著增加,差异有统计学意义(P<0.01)。常规治疗组不良反应发生率明显大于间歇治疗组,差异有统计学意义(P<0.01)。结论小剂量间歇补铁法能有效治疗IDA,且药物副作用少、依从性好。
Objective To study the curative and side effects of small dose of iron supplements on the inter-mittent treatment for children with iron deficiency anemia （ IDA） .Methods 133 children with IDA were divided into two groups, respectively given A group（small doses of intermittent iron supplements） and B group（regular daily dose iron supplement as control group）.After two months′treatment, serum ferritin（SF） and hemoglobin（Hb） were de-tected and adverse reactions were observed in the two groups .Results SF and Hb were same after treatment .They were significantly elevated in both groups （ P〈0.01 ） .There was no significantly difference between two groups after treatment（P〉0.05）.The adverse reaction rate of B group was obviously higher than that of A group （P〈0.01）. Conclusion Small dose of iron supplements of intermittent treatment for the children with IDA is effective and has lower side effects .
出处
《中国临床新医学》
2015年第4期349-351,共3页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
