摘要
目的:探讨阿奇霉素采用不同用药方式治疗小儿支原体感染的临床疗效。方法:随机抽取166例本院2013年1-12月收治的小儿支原体感染患儿作为本次研究对象,按随机双盲法分为观察组与对照组,对照组患儿83例,采用常规治疗方法的基础上,首次剂量为20 mg/kg阿奇霉素注射液静脉滴注,持续用药5 d,1次/d,后4 d用药量为首次的一半,停药4 d后,再次治疗3 d。观察组患儿83例其他同上,在患儿停药4 d后,再次治疗5 d。治疗结束后,对两组患儿的临床疗效、住院时间及各种病症消失时间进行比较。结果:观察组患儿的痊愈率及总有效率分别为84.3%(70例)、95.1%(79例),对照组分别为79.5%(66例)、91.5%(76例),两组比较差异无统计学意义。观察组患儿住院时间及各种症状消失时间均低于对照组,比较差异有统计学意义(P<0.05)。结论:采用阿奇霉素对患儿进行静脉滴注治疗5 d后,停药4 d,再次治疗5 d,能有效缩短患儿的住院时间及各种疾病的消失时间,得到了患儿家属的一致好评,值得在临床上进行推广。
Objective： To discuss the clinical curative effect of using different treatment method of azithromycin treatment of children with Mycoplasma infection. Method： 166 patients with mycoplasma infection in our hospital from 2013 January to December were randomly selected as the objects, and randomly divided into observation group and control group, the control group contained 83 cases, which was given treatment of azithromycin based conventional treatment methods ： the first dose of 20 mg/kg Azithromycin injection, intravenous infusion of the drug, sustained 5D, 1 time/d, after 4D dosage for the first half, after 4D of withdrawal, again in the treatment of 3D by using this method; the observation group contained 83 cases, which carries on the treatment method using the same control group based on the conventional treatment, difference was that, stop drug 4D in children, again in the treatment of 5D using this method. At the end of treatment, the clinical efficacy, duration of hospitalization, and various symptoms disappear time of the two groups was compared. Result： The cure rate and total effective rate of the observation group was 84.3% （ 70 cases ）, 95.1% （ 79 cases ）, and that of the control group was 79.5% （ 66 cases ）, 91.5% （ 76 cases ）, there was no statistically significant difference. The hospitalization time and a variety of diseases disappear time of the observation group was lower than that of the control group, there was statistically significant difference （P〈0.05） . Conclusion： The use of azithromycin intravenous infusion therapy for children with 5D after stopping drug, 4D, again in the treatment of 5D by using this method, can effectively shorten the symptom disappearance time, get fav, orable comments from the families of the children, worthy of promotion and application in clinical.
出处
《中国医学创新》
CAS
2015年第10期48-50,共3页
Medical Innovation of China
关键词
小儿
支原体感染
阿奇霉素
Children
Mycoplasma infection
Azithromycin
