摘要
目的探讨妊娠期母体的雌激素和5-HT水平与抑郁症的关系。方法选择2013年7月~2014年7月到我院就诊的处于妊娠期的抑郁症患者40例作为观察组,并同期选择40例精神状态健康的妊娠期妇女作为对照组。对患者进行HAMD、HAMA量表的检测,观察2组患者之间的雌激素以及5-HT水平情况。结果观察组患者的HAMD、HAMA评分明显的高于对照组患者,观察组患者的E2、5-HT远低于对照组患者;观察组妊娠妇女的正常妊娠率（75%）低于对照组妊娠妇女的正常妊娠率（92.5%）,2组之间的差异存在显著性（P〈0.05）。结论对妊娠期妇女的E2、5-HT进行检测,可以有效的对妊娠期妇女的抑郁情况进行观察分析,以提高妊娠效果。
Objective To investigate the relationship between gestational maternal estrogen and 5-HT levels with depression. Methods Choosing 40 women in our hospital treat with depression in pregnancy from July in the2013 to July in the 2014 as the observation group,and select the same period 40 cases of healthy mental state of pregnant women as control group. HAMD,HAMA scale detection in patients with selected patients,observation group 2 patients between estrogen and 5-HT level. Results The patients in the observation group were HAMD,HAMA score was significantly higher than the patients in the control group,patients in the observation group E2,,5-HT far lower than that of the control group of patients with E2,5-HT; 2 groups of women in pregnancy pregnancy,pregnancy rate in observation group（ 75%） was significantly lower than the control group of pregnant women with normal pregnancy rate（ 92. 5%）,significant differences exist between the 2 groups（ P 〈 0. 05）. Conclusion Detection of pregnant women of the E2,5-HT,can be effective for pregnant women of the depression were analyzed,in order to improve the effect of pregnancy.
出处
《国际精神病学杂志》
2015年第2期24-26,共3页
Journal Of International Psychiatry
