摘要
目的:分析阿奇霉素在儿科治疗中的不良反应与临床用药。方法:选取2011年3月—2013年12月间儿科诊治的患者140例,将其按照年龄、病情、性别等随机分为对照组和治疗组(各70例);对照组患者给予阿奇霉素注射治疗,治疗组患者给予口服阿奇霉素口服治疗;比较两组患者不良反应的发生情况。结果:两组患者不良反应的发生情况,如过敏性休克、过敏性皮疹、发烧、肠胃不适等发生率经比较其差异无统计学意义(P>0.05)。结论:阿奇霉素在儿科临床使用中出现不良反应的情况与患者的用药途径关系不大,采用口服、静脉滴注方式给药都会引起不良反应,因此临床治疗中应对阿奇霉素治疗中出现的不良反应予以预防和治疗。
Objective： To analyze the adverse drug reactions of azithromycin and clinical medication in pediatrics. Methods： 140 cases of patients were selected during March 2011 to December 2013 in pediatrics. Based on age, gen- der patients were randomly divided into control group（n=70） and experimental group（n=70）. The control group was treated by injection of azithromycin, test group was treated with oral azithromycin. Prevalence of adverse reactions of two groups of patients was comparsed. Results： The two groups of patients with adverse reactions occurrence such as al- lergic shock, allergic skin rash, fever, gastrointestinal discomfort incidence were not statistically significant （P〉0.05）. Conclusion： Patients with azithromycin had adverse reactions in＇the pediatric clinical applicatio. It was not associated with route of administration, both oral and intravenous drip method would cause adverse reactions. Therefore in clinical practive the adverse reactions of azithromycin should be prevented.
出处
《抗感染药学》
2015年第2期189-192,共4页
Anti-infection Pharmacy
