摘要
目的:为抗栓治疗诱发药源性血小板减少症患者药学监护提供参考。方法:临床药师通过参与2例分别由低分子肝素、盐酸替罗非班致药源性血小板减少症典型案例分析,给予药学建议,分别为换用磺达肝癸钠注射液2.5 mg,ih,qd,同时给予甲泼尼龙200 mg,输注血小板2 u;停用盐酸替罗非班,口服阿司匹林、氯吡格雷,连续3 d分别输注血小板1 u、甲泼尼龙200 mg。结果:临床药师协助判断血小板减少症的病因并给予适当处理后患者血小板逐渐恢复正常,病情缓解出院。结论:临床药师参与抗栓诱发药源性血小板减少症患者的药学监护,能有效改善患者预后,保障患者的用药安全。
OBJECTIVE： To provide reference for the pharmaceutical care of patients with drug-induced thrombocytopenia in- duced by antithrombotic. METHODS ： Clinical pharmacists participated in 2 cases of drug-induced thrombocytopenia respectively in- duced by low molecular weight heparin and tirofiban and made individual treatment regimens. The treatment regimen for the one case was fondaparinux sodium injection 2.5 rag, ih, qd, with methylprednisolone 200 mg and platelets 2 u; the treatment of anoth- er case was tirofiban hydrochloride withdrawl and orally given aspirin and clopidogrel for 3 d with platelets 1 u and methylpredniso- lone 200 rag. RESULTS： After clinical pharmacists＇ assistance to the judging the etiology of thrombocytopenia and proper treat- ment, the platelet of patients gradually returned to normal and discharged. CONCLUSIONS： Clinical pharmacists participating in the pharmaceutical care of patients with drug-induced thrombocytopenia induced by antithrombotic can effectively reduce the progno- sis of patients and ensure the drug safety of patients.
出处
《中国药房》
CAS
北大核心
2015年第14期1979-1981,共3页
China Pharmacy
基金
河南省教育厅科学技术研究重点项目(No:12A350006)
