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维生素D与慢性肾脏病的研究进展 被引量：1

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摘要 维生素D（VD）是脂溶性维生素，属于类固醇化合物。VD的经典作用是调节钙磷代谢，维持机体钙磷平衡。最近的研究还发现活性VD3及其类似物可以通过抑制系膜细胞增殖、细胞外基质沉积、抑制炎性细胞活化、炎性因子分泌以及抑制肾素表达，降低肾素一血管紧张素系统（RAS）活性而减轻肾脏滤过压、减轻足细胞损伤而减轻蛋白尿，缓解胰岛素抵抗等诸多途径达到保护肾脏的作用。
作者 权志慧 夏成云
机构地区 川北医学院附属医院肾内科
出处 《国际泌尿系统杂志》 2015年第3期472-475,共4页 International Journal of Urology and Nephrology
关键词 肾疾病 维生素D
分类号 R692 [医药卫生—泌尿科学]
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参考文献41

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二级参考文献98

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国际泌尿系统杂志
2015年 第3期

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