摘要
目的：探讨采用双水平正压通气治疗小儿重症毛细支气管炎的临床疗效。方法选取2011年12月-2014年10月本院收治的97例重症小儿毛细支气管炎患儿，分为治疗组（48例）和常规组（49例），常规组给予抗感染、平喘、雾化吸痰、糖皮质激素等治疗，治疗组在常规组治疗基础上采用双水平正压通气进行辅助治疗，比较两组患儿的临床症状缓解时间、治疗3d后的临床效果及动脉血气分析变化差异。结果治疗组患儿心率好转时间、呼吸困难消失时间、肺部湿啰音消失时间均显著短于常规组，差异有统计学意义（P〈0.05）。治疗3 d后，治疗组患儿的HR（112.9±13.6/min）、pH值（7.32±0.09）、PaO2[（85.6±9.4） mm Hg]、PaCO2[（48.4±6.4） mm Hg]、PaO2/FiO2[（221.3±16.5）mm Hg]均显著优于常规组，差异有统计学意义（P〈0.05）；治疗组临床疗效分布显著优于常规组，差异有统计学意义（P〈0.05）；治疗组的总有效率（93.75%）显著高于常规组（77.08%），差异有统计学意义（P〈0.05）。结论双水平正压通气治疗能改善小儿重症毛细支气管炎的临床症状，纠正血气指标，提高临床疗效。
Objective To explore the clinical efficacy of bi-level positive airway pressure （BiPAP） on treating children with severe capillary bronchitis. Methods 97 children with severe capillary bronchitis in our hospital from December 2011 to October 2014 were selected and divided into treatment group（n=48） and conventional group（n=49）.Therapies of anti-infection,panting alleviation,atomization suctioning and glucocorticoid were adopted in conventional group;while on the basis of conventional group,BiPAP as an adjuvant therapy was applied in treatment group.The alleviation time of clinical symptoms,clinical efficacy after 3 d treatment,and difference of arterial blood gas between two groups were compared. Results Time of heart rate improving,disappearing of dyspnea,disappearing of pulmonary moist rales in treat-ment group were greatly shorter than that in conventional group,with statistical differences （P〈0.05）.In treatment group, HR （112.9±13.6/min）,pH value （7.32±0.09）,PaO2 [（85.6±9.4） mm Hg],PaCO2 [（48.4±6.4） mm Hg],and PaO2/FiO2 [（221.3±16.5） mm Hg] which were all superior to that in conventional group,with statistical differences（P〈0.05）.Clinical efficacy after 3 d treatment in treatment group was superior to that in conventional group,with statistical difference （P〈0.05）.The total effective rate in treatment group was 93.75%,higher than that in conventional group accounting for 77.08%,with a statistical difference （P〈0.05）. Conclusion BiPAP can improve clinical symptoms and signs of severe capillary bronchi-tis in children and rectify blood gas index in order to improve clinical efficacy.
出处
《中国当代医药》
2015年第13期45-47,共3页
China Modern Medicine
关键词
双水平正压通气
小儿重症毛细支气管炎
临床疗效
Bi-level positive airway pressure （BiPAP）
Children with severe capillary bronchitis
Clinical efficacy
