摘要
目的探讨心脏外科手术后急性肾衰竭（ARF）的治疗方法及疗效。方法回顾性分析2004年1月-2014年1月在解放军总医院心外科行心脏外科手术后发生ARF的54例患者的临床资料,其中男35例,女19例,年龄1个月~79岁,中位年龄52岁。行冠状动脉旁路移植术（CABG）10例,瓣膜手术22例,CABG＋瓣膜手术4例,主动脉手术14例,法洛四联症根治术4例。50例采用床旁连续肾脏替代疗法（CRRT）治疗,4例采用腹膜透析治疗。结果住院期间死亡9例,病死率16.7%,术后开胸探查止血8例,拔管失败4例。9例死亡患者中6例死于多脏器功能衰竭,2例死于脑出血,1例死于急性呼吸衰竭。采用CRRT及腹膜透析治疗后,血肌酐（SCr）和血尿素氮（BUN）下降明显（P〈0.05）;所有患者治疗过程中血流动力学稳定,未发现出血或栓塞等并发症。结论心脏外科手术后ARF应早期发现、及时处理,CRRT及腹膜透析是治疗心脏外科手术后ARF安全、方便、有效的方法,可降低病死率。
Objectives To evaluate the result of treatment of acute renal failure（ARF） in patients after cardiac surgery. Methods The clinical data of 54 cases admitted to the hospital from Jan. 2004 to Jan. 2014 and suffered from ARF after cardiac surgery were retrospectively analyzed. Among 54 cases, there were 35 males and 19 females, aged from one month to 79 years with a median of 52 years. The surgical procedures included coronary artery bypass grafting（CABG, 10 cases）, valve surgery（22 cases）, combined CABG and valve surgery（4 cases）, operation on aorta（14 case）, and radical correction of Fallot tetralogy（4 cases）. After the operations mentioned above, 50 patients received continuous renal replacement therapy（CRRT）, and 4 patients received peritoneal dialysis. Results Nine patients died, the mortality rate was 16.7%. Exploratory hemostasis by thoracotomy was performed in 8 patients, and extubation failure occurred in 4 cases. Of the 9 non-survivors, 6 died from multiple organ failure（MOF）, 2 died from cerebral hemorrhage, and one died from acute respiratory failure. Serum creatinine（SCr） and blood urea nitrogen（BUN） levels declined obviously after CRRT and peritoneal dialysis（P〈0.05）, and all the patients were shown to have stable hemodynamics in the course of treatment, and no hemorrhage or embolism occurred. Conclusions ARF after cardiac surgery should be detected early and treated in time. CRRT and peritoneal dialysis are safe, convenient and effective procedures, and may decrease the mortality rate in patients with ARF after cardiac surgery.
出处
《解放军医学杂志》
CAS
CSCD
北大核心
2015年第4期319-321,共3页
Medical Journal of Chinese People's Liberation Army
关键词
心脏外科手术
急性肾损伤
肾替代疗法
cardiac surgical procedures
acute kidney injury
renal replacement therapy
