摘要
目的：观察双心医学诊疗模式在慢性心力衰竭（CHF）合并焦虑抑郁患者中的疗效。方法采用《躯体化症状自评量表》筛查C H F患者，得分在38～42存在轻中度焦虑抑郁的70例患者入选，按随机数字表法分为治疗组（35例）和对照组（35例），2组均采用正规的抗心力衰竭治疗方案，治疗组再加用氟哌噻吨美利曲辛片1粒（0.5 mg／10 mg），早、中各1次，疗程3个月。2组治疗前后均进行躯体化症状自评量表评分、美国纽约心脏病学会（NYHA）心功能分级评定、心脏超声检查、6 min步行试验（6MWT）及检测血浆B型脑钠肽（BNP）值。结果与治疗前相比，治疗组总有效率为86％，对照组为60％，2组比较差异有统计学意义（ P＜0.05）。2组治疗后心脏超声指标[左心室舒张末内径（（LVEDD）、左心室射血分数（LVEF）]、6 min步行距离（6MWD），BNP、躯体化症状自评量表评分均较治疗前改善，差异有统计学意义（ P ＜0．05）；与对照组相比，治疗组治疗后在心功能分级改善、6MWT距离的提高、BNP和躯体化症状自评量表评分下降更明显，差异有统计学意义（ P ＜0．05）。结论双心医学诊疗模式对于慢性心力衰竭合并焦虑抑郁的患者可明显改善心脏功能，提高患者的生活质量。
Objective The aim of this study was to evaluate the effectiveness of psycho‐cardiology treatment mode in the patients with chronic heart failure （CHF） complicated with anxiety‐depression.Methods Seventy CHF patients with mild to moderate anxiety‐depression （scores between 38‐42） were selected and randomly divid‐ed into treatment group （ n=35） and the control group （ n=35）based on criteria of the Somatic Self‐rating Scale （SSS） classification .The regular anti heart failure treatment scheme was used in two groups ,but the treatment group was combined with Flupentixol and melitracen tablets （0.5 mg/10 mg ） one tablet each time ,two times （morning and afternoon） a day ,the course of treatment was 3 months .The score of SSS ,the examination of car‐diac color Doppler ultrasound ,6‐min walk test （6MWT） ,B‐type natriuretic peptide（BNP） in plasma were carried out and cardiac function classification was calculated according to NYHA before and after treatment in two groups.Results Compared with before treatment ,the total effective rate of treatment group was 86% ,while that in the control group was 60% . There were significant differences （ P〈 0.05 ） . Echo‐cardiographic indexes （LVEDD ,LVEF） ,6MWT ,BNP ,SSS scores were improved after treatment compared with before treatment （P〈0.05） in the two groups .Compared with the control group ,there were improved cardiac function classification , increased 6MWT distance and decreased BNP .SSS scores in the treatment group were of statistical significance （P〈0.05） .Conclusion It is suggested that psycho‐cardiology treatment mode can significantly improve the heart function and quality of life in patients with chronic heart failure （CHF） complicated with anxiety‐depression .
出处
《山西医药杂志》
CAS
2015年第9期985-988,共4页
Shanxi Medical Journal
关键词
双心治疗
心力衰竭
慢性
心脏功能
Psycho-cardiology treatment mode
Heart failure,chronic
Cardiac function
