摘要
目的探究分析妊娠合并糖尿病患者发生抑郁情况的影响因素。方法 160例妊娠合并糖尿病患者作为试验组,随机选取同期入院的160例正常孕妇作为对照组。采用抑郁自评量表(SDS)对所有患者进行抑郁情况评分,并记录比较两组患者抑郁发生率,采用Logistic回归分析妊娠合并糖尿病患者发生抑郁的影响因素。结果多因素Logistic回归分析结果显示,并发症、年龄、社会支持(SSRS)总分是2型糖尿病(T2DM)患者合并抑郁的影响因素,OR值分别为1.892、0.672、0.558;试验组患者糖化血红蛋白水平、妊娠期抑郁发生率及SDS评分情况均明显高于对照组,组间比较差异有统计学意义(P<0.05);回归分析结果显示,孕妇年龄、体质量指数(BMI)、不良孕史、糖尿病病程以及孕期糖化血红蛋白水平在一定程度上均与抑郁的发生有关(P<0.05)。结论妊娠合并糖尿病患者在妊娠期间易发生抑郁,患者糖化血红蛋白含量与抑郁程度明显相关,而抑郁情况与妊娠结局息息相关,采用有效方法控制孕妇血糖值,改善抑郁状态,对于改善妊娠结局有积极意义。
Objective To investigate and analyze the influence factors of depression in gestation complicated with diabetes mellitus patients.Methods There were 160 gestation complicated with diabetes mellitus patients in experimental group, and another 160 healthy pregnant women in the same admission period in control group. Self-rating depression scale （SDS） was applied for grading depression status in all patients, and records were made on incidences of depression for comparison between the two groups. Influence factors of depression in gestation complicated with diabetes mellitus patients were analyzed by Logistic regression.Results Multivariate Logistic regression showed that complications, age and total score of social support rating scale （SSRS） were the influencing factors of type 2 diabetes mellitus （T2DM） complicated with depression patients, and their OR values were 1.892, 0.672, and 0.558. The experimental group had much higher glycosylated hemoglobin level, incidence of gestational depression, and SDS level than the control group, and the difference between the two groups had statistical significance （P〈0.05）. Logistic regression results showed certain correlation in depression and maternal age, body mass index （BMI）, bad pregnancy history, duration of diabetes mellitus, and gestational glycosylated hemoglobin level （P〈0.05）.Conclusion Depression is easily occurred in gestation complicated with diabetes mellitus patients. Their depression degree is obviously related with glycosylated hemoglobin level, and depression statue has correlation with pregnancy outcome. Implement of effective blood glucose control method can improve depression status, and that contains positive significance for improving pregnancy outcome.
出处
《中国现代药物应用》
2015年第12期15-17,共3页
Chinese Journal of Modern Drug Application
关键词
妊娠
糖尿病
抑郁
影响因素
Gestation
Diabetes mellitus
Depression
Influence factors
