期刊文献+

咖啡酸体外抗氧化活性的研究 被引量:83

Studies on the Antioxidant Activity in Vitro of Caffeic Acid
原文传递
导出
摘要 咖啡酸是一种天然的酚类化合物,属于羟基肉桂酸类,它广泛存在于水果和蔬菜中,具有良好的生物活性。本文通过多种体系对咖啡酸的抗氧化活性进行综合评价,包括总抗氧化能力、DPPH自由基清除活性、ABTS自由基清除活性、铁离子还原能力和金属离子螯合能力等。结果表明:咖啡酸具有很强的总抗氧化能力,极显著高于BHT和VC(P<0.01);具有较强的DPPH自由基(IC500.023 mg/m L±0.004 mg/m L)和ABTS自由基(IC500.18 mg/m L±0.006 mg/m L)清除活性;具有较强的铁离子还原能力并极显著高于BHT(P<0.01)。咖啡酸几乎不具备金属离子螯合能力。 Caffeic acid is a natural phenolic compound that belongs to hydroxy cinnamic acid being widely found in fruits and vegetables with good biological activity. To evaluate its antioxidant activity, a variety of systems applied in- cluding the total antioxidant capacity, DPPH free radicals scavenging activity, ABTS free radicals scavenging activity, ferric reducing ability and ferrous ions chelating activity were employed for the evaluation. The results indicate that caffeic acid showed a strong total antioxidant capacity that was very significantly higher than BHT and VC(P〈0.01 ), and that was further proved by a strong DPPH radical (IC50 0.023 ± 0.004 mg/mL) and ABTS radical (IC50 0.18 ±0.006 mg/mL) scavenging activity and a strong ferric reducing ability significantly higher than BHT (P〈0.01). Nevertheless, caffeic acid almost did not have ferrous ions chelating activity.
出处 《中国食品学报》 EI CAS CSCD 北大核心 2015年第3期65-73,共9页 Journal of Chinese Institute Of Food Science and Technology
关键词 咖啡酸 总抗氧化能力 DPPH ABTS 铁离子还原能力 金属离子螯合能力 Caffeic acid total antioxidant activity DPPH ABTS Ferric ions reducing power Ferrous ions chelating activity
  • 相关文献

参考文献29

  • 1Valko M, Rhodes C, Moncol J, et al. Free radicals, metals and antioxidants in oxidative stress-induced cancer[J]. Chemico-Biological Interactions, 2006, 160(1): 1-40.
  • 2Gulcin i, Mshvildadze V, Gepdiremen A, et al. The antioxidant activity of a triterpenoid glycoside isolated from the berries of Hedera colchica: 3 - O - (/3 - d - glucopyranosyl) - hederagenin[J]. Phytotherapy Research, 2006, 20 (2) : 130-134.
  • 3Visioli F, Lastra CADL, Andres-Lacueva C, et al. Polyphenols and human health: a prospectus[J]. Critical Reviews In Food Science And Nutrition, 2011, 51(6): 524-546.
  • 4Aytekin AO, Morimura S, Kida K. Synthesis of chitosan-caffeic acid derivatives and evaluation of their antioxidant activities[J]. Journal Of Bioscience And Bioengineering, 2011, 111(2): 212-216.
  • 5Liu RH. Potential synergy of phytochemicals in cancer prevention: mechanism of action[J]. The Journal of nutrition, 2004, 134(12) : 3479S-3485S.
  • 6Papandreou MA, Dimakopoulou A, Linardaki ZI, et al. Effect of a polyphenol-rich wild blueberry extract on cogni- tive performance of mice, brain antioxidant markers and acetylcholinesterase activity[J]. Behavioural Brain Research, 2009, 198(2): 352-358.
  • 7Naczk M, Shahidi F. Phenolics in cereals, fruits and vegetables: Occurrence, extraction and analysis[J]. Journal of Phar- maceutical And Biomedical Analysis, 2006, 41(5): 1523-1542.
  • 8Popa VI, Dnmitrn M, Volf I, et al. Lignin and polyphenols as allelochemicals[J]. Industrial Crops and Products, 2008, 27(2) : 144-149.
  • 9王俏,邹阳,钟耕,罗金华.多酚类单体物质抗氧化活性的研究[J].食品工业科技,2011,32(1):137-140. 被引量:37
  • 10Prieto P, Pineda M, Aguilar M. Spectrophotometric quantitation of antioxidant capacity, through the formation of a phosphomolybdenum complex: specific application to the determination of vitamin E[J]. Analytical Biochemistry, 1999, 269(2): 337-341.

二级参考文献68

  • 1张俊苓,邹家浩,郑文杰,杨芳,白燕,李毅群.硒芳香杂环化合物的微波固相合成[J].化学研究与应用,2004,16(4):561-562. 被引量:5
  • 2邹家浩,郑文杰,杨芳,曾鑫华,白燕,李毅群.硒芳香杂环化合物的GC/MS分析[J].分析科学学报,2005,21(4):381-383. 被引量:2
  • 3Surh Y J.Nat.Rev.Cancer,2003,3:768.
  • 4Rayman M P.Lancet,2000,356:233.
  • 5El-Bayoumy K,Sinha R.Mutation Res.,2004,551:181.
  • 6Tapiero H,Townsend D M,Tew K D.Biomed.Pharmacother.,2003,57:134.
  • 7Abdulah R,Miyazaki K,Nakazawa M,et al.J.Trace.Elem.Med.Biol.,2005,19:141.
  • 8Zhang J L,Zheng W J,Zou J H,et al.Chem.J.Int.,2004,6:97.
  • 9Chen T F,Wong Y S,Zheng W J,et al.Chemico-Biological Interact.,2009,180:54.
  • 10Chen T F,Zheng W J,Wong Y S,et al.Biomed.Pharmacother.,2008,62:77.

共引文献94

同被引文献1090

引证文献83

二级引证文献484

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部