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四磨汤对便秘肠道微生态调节作用的研究 被引量:11

Regulatory effect of Simo decoction on intestinal microecology in constipation
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摘要 便秘是一种常见的胃肠功能失调症,多见于儿童和老年人。便秘时肠道菌群发生了显著改变,有害细菌或条件致病菌数量增加和有益菌数量减少。四磨汤是临床上广泛使用的中药胃动力剂,能缓解便秘患者的症状和身心压力,且对便秘患者肠道微生态的平衡恢复具有明显的调控作用。本研究从便秘时肠道的微生态改变、单味药和整方的角度探讨四磨汤调节肠道微生态的作用机制。 Constipation as a common gastrointestinal function disorder is often seen among children and the elder- ly. Generally, constipation causes significant changes in gut mieroflora with the decrease of probiotics and increase of harmful or opportunistic pathogenic bactoria. Simo decoction is a kind of traditional Chinese medicine widely used clinically as a gastric motility drug, which can alleviate the symptoms, reduce the mind body stress of pa- tients, and regulate the balance of gastric microecology. This study focused on the change of intestinal mierobiota in constipation and discussed how Simo decoction effectively recover the intestinal microbiota in constipation based single and compound prescriptions of the traditional Chinese herbal medicine.
出处 《中国微生态学杂志》 CAS CSCD 2015年第5期614-617,共4页 Chinese Journal of Microecology
基金 国家自然科学基金资助项目(81302952)
关键词 四磨汤 便秘 肠道微生态 益生菌 调节作用 Simo decoction Onstipation Microecology Probiotics Moderating role
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