摘要
目的:探讨抑郁症患者神经内分泌与临床特征的相关性。方法:采用汉密尔顿抑郁量表(HAMD)和对神经内分泌数据的收集,进行分析。结果:下丘脑-垂体-甲状腺轴(HPT)正常组与异常组体重因子(t=-2.941,P<0.01)和睡眠因子(t=-1.996,P<0.05)有显著性差异;促甲状腺激素(TSH)高于正常组、低于正常值组与正常值组躯体性焦虑因子(F=3.024,P<0.05)和阻滞因子(F=3.378,P<0.05)有显著性差异,TSH低于正常值组的躯体性焦虑严重于TSH正常组(P<0.05),TSH低于正常值组的阻滞严重于TSH高于正常值组(P<0.05)。结论:下丘脑-垂体-甲状腺轴(HPT)正常组体重减轻低于异常组;促甲状腺激素(TSH)低于正常值组的躯体性焦虑严重于TSH正常组,TSH低于正常值组的阻滞严重于TSH高于正常值组。
Objective： To explore the relation between neuroendocrine and clinical features in patients with depression. Methods： Hamilton Depression Scale（ HAMD） and neuroendocrine data collection were conducted on the patients with depression. Results： The normal HPT group and abnormal HPT group were different in weight factor（ t =-2. 941,P〈0. 01） and sleep factor（ t =-1. 996,P〈0. 05）; Patients with different thyroid- stimulating hormone（ TSH） were different in the somatic anxiety factor（ F = 3. 024,P〈0. 05） and retardation factor（ F = 3. 378,P〈0. 05）. Patients with lower TSH had more somatic anxiety those with normal TSH（ P〈0. 05）,and more block than the normal group（ P〈0. 05）. Conclusion：Patients with normal HPT has less weight loss than abnormal group; Patients with less TSH have more somatic anxiety and block than the normal group.
出处
《中国健康心理学杂志》
2015年第6期814-816,共3页
China Journal of Health Psychology
