摘要
目的探讨分析血凝酶在肺癌根治术中局部应用的止血效果。方法选取该院自2011年5月—2014年2月间,同一主刀医师所作肺癌根治手术92例,皆为肺叶切除加淋巴结清扫,随机分为两组,一组为对照组,(46例)术中创面未使用凝血酶。凝血酶组(46例)术中取血凝酶4单位加入20 mL生理盐水中,向操作创面喷雾覆盖。术后观察病人的全身反应、生命体征,记录术后第1、2、3天的胸引量、胸水红细胞计数等。结果两组病人无明显全身反应,生命体征皆平稳,无差异。凝血酶组与对照组比较,胸引量(324.7±87.9)、(402.6±82.7)mL/d,平均胸水红细胞计数(2.5±0.7)、(5.9±1.2)×105/L。两组比较均有统计学意义(P<0.05)。结论 在肺叶切除加淋巴清扫术,关胸前向手术创面喷洒凝血酶,能明显减少术后胸腔引流量、缩短大部分病人术后带管时间。
Objective To observe the reptilase hemostatic effect of local application in radical resection of lung cancer. Methods From may 2011 to February 2014, the author had treated 92 cases of lung cancer patients,they were all treated with lobectomy and lymph node cleaning. The 92 patients undergoing lung cinoma operation were divided into two groups randomly：Group A （ n =46） without received reptilase during and after operation, Group B（n=46） received reptilase 4 units with 20 ml saline solution to spray operation wound. The patient＇s postoperative systemic reactions and vital signs were observed, at the same time,the volume of pleural effusion and the amount of red blood cells at 1,2 and 3 days after operation were observed. Results There was no signifi-cant difference between Group A and Group B in the patient＆#39;s postoperative systemic reactions and vital signs. The volume of pleural effusion and amount of red blood cells of group B at 1,2 and 3 days after operation we re less than group A（P〈0.05）. Con-clusion In lung resection with lymph node cleaning, spraying thrombin closed chest to the surgical wound, It can obviously re-duced the The volume of pleural effusion and amount of red blood cells,shortened the time of drainage tube in body.
出处
《中外医疗》
2015年第8期141-142,共2页
China & Foreign Medical Treatment
关键词
血凝酶
局部应用
肺癌根治术
Reptilase
Topical application
Radical resection of lung cancer
