摘要
目的探讨带状疱疹后遗神经痛的相关危险因素。方法选择我院2012-07—2014-07诊治的带状疱疹患者213例。按是否出现神经痛分为带状疱疹后神经痛组和带状疱疹后无神经痛组。比较2组性别、年龄、焦虑或抑郁状态、皮疹部位、急性期疼痛程度,对各主要研究因素进行单因素分析,对差异有统计学意义的因素再进行多因素Logistic回归分析。结果单因素分析显示,2组患者年龄≥50岁、女性、有焦虑或抑郁状态、急性期重度疼痛4个因素上,差异有统计学意义(P<0.05);2组皮疹部位比较差异无统计学意义(P>0.05)。多因素Logistic回归分析显示,年龄≥50岁、女性、急性期重度疼痛进入回归模型(P<0.05)。结论年龄≥50岁、女性、急性期重度疼痛为影响带状疱疹后遗神经疼痛的独立危险因素,重视高年龄、女性及急性期重度疼痛患者早期给予抗病毒及抗病理神经痛可有效预防疱疹后神经痛。
Objective To analyze the risk factors for post‐herpetic neuralgia. Methods 213 patients with herpes zoster in our hospital from July 2012 to July 2014 were selected. According to whether there is neuralgia ,they were divided into post‐herpetic neuralgia group and non‐neuralgia group. The gender ,age ,anxiety or depression ,rash site ,the degree of acute pain of two groups were compared ,the main factors conducted univariate analysis ,and the factors with statistical differences carried on further multivariate Logistic regression analysis. Results Univariate analysis revealed that patients with ≥50 years of age , female ,anxiety or depression ,severe pain in the acute phase were the four factors （P〈0.05）;and the rash of the two groups had no statistically significant difference （P〉0.05）. Logistic regression analysis revealed that age ≥50 years old ,female ,a‐cute phase of severe pain in the regression model （P〈0.05）.Conclusion Age ≥50 years old ,female ,severe pain in the acute phase of three factors are independent risk factors affecting nerve pain after shingles. Pay attention to high age and female ,and acute phase of severe pain in patients with early disease management and administration of an anti‐virus neuralgia can be effec‐tive in preventing post‐herpetic neuralgia.
出处
《中国实用神经疾病杂志》
2015年第11期20-22,共3页
Chinese Journal of Practical Nervous Diseases
