摘要
目的评估经皮冠状动脉介入治疗（PCI）患者术后血栓弹力图（TEG）指标对其预后的预测作用。方法收集115例PCI患者资料,根据其TEG报告中二磷酸腺苷（ADP）诱导的最大血块强度（MA-ADP）将患者分为MA-MDP〈50 mm组和≥50 mm组,随访观测其1年后心血管不良事件和支架再梗死及再狭窄的发生率。结果根据MA-ADP分组的2组患者的临床基本情况差异无统计学意义（P〉0.05）。Logistic回归分析显示MA-ADP是PCI术后患者心血管不良事件复发风险的危险因素[OR=3.547（95%CI：1.103-11.412）,P=0.034]。与MA-ADP正常（〈50 mm）的患者相比,MA-ADP升高（≥50 mm）的患者的心血管不良事件和支架内再梗死的发生率均明显升高（P均〈0.05）。结论 MA-ADP对PCI术后患者的预后有预测作用,MA-ADP=50 mm可作为PCI术后患者心血管不良事件复发风险的判断切点。
Objective To evaluate the prognosis prediction of thrombelastography（ TEG） in patients undergoing percutaneous coronary intervention（ PCI）. Methods The data from 115 patients undergoing PCI were collected,and the patients were classified into 2 groups according to maximum amplitude-adenosine diphosphate（ MA-ADP）,MA-MDP 50 mm group and MA-ADP≥50 mm group. The percentages of adverse cardiovascular events,reinfarction and restenosis were followed up for 1 year. Results There was no statistical significance in the clinical characteristics of the 2 groups（ P〈0. 05）. Logistic regression analysis showed that MA-ADP was the risk factor of adverse cardiovascular event recurrence in patients undergoing PCI（ OR = 3. 547,95% CI： 1. 103-11. 412,P = 0. 034）. Compared with MA-ADP normal patients（ 〈50 mm）,the incidences of adverse cardiovascular events and reinfarction in patients with high MA-ADP（ ≥50 mm） significantly increased（ P〈0. 05）. Conclusions MA-ADP can predict the prognosis after PCI. MA-ADP = 50 can be the cut-off point in the prognosis prediction of patients undergoing PCI.
出处
《检验医学》
CAS
2015年第6期571-574,共4页
Laboratory Medicine
基金
"十二五"国家科技支撑计划课题资助项目(2012BAI37B01)
上海市卫生系统先进适宜推广技术项目(2013SY065)
国家临床重点检验专科建设项目资助
关键词
血栓弹力图
经皮冠状动脉介入治疗
ADP诱导的最大血块强度
心血管不良事件
预后判断
Thrombelastography
Percutaneous coronary intervertion
Maximum amplitude-adenosine diphosphate
Adverse cardiovascular event
Prognosis prediction
