摘要
目的:分析34例肾康注射液不良反应报告,为临床用药提供指导。方法:对34例使用肾康注射液发生不良反应病例的年龄分布、不良反应发生的时间、表现、处理以及预后情况进行分析。结果:使用肾康注射液发生不良反应的34例患者中,年龄>50岁的患者不良反应发生率较高;79.41%不良反应发生在给药后30 min内,连续多天给药仍可能出现不良反应;不良反应表现以皮肤过敏反应多见,部分患者表现为发热、全身发抖、胸闷、呼吸急促、耳鸣等;采用地塞米松或盐酸异丙嗪治疗效果好。结论:使用肾康注射液时,应密切观察患者反应,若出现不良反应,应立即停药,采用地塞米松、盐酸异丙嗪等进行抗敏治疗。
Objective: To investigate 34 cases of adverse reactions after Shenkang injection that aims to provide effective guidance for clinical treatment. Methods: Analyzing 34 cases in terms of age distribution,recorded time of adverse reaction,expression,treatment and prognosis. Results: Of all the patients injected with Shenkang,patients older than 50 exhibited higher incidence rate of adverse reactions; 79. 42% of adverse reaction occurred within 30 min of injection,continuous medication for days might still cause adverse reaction; clinical adverse reactions of Shenkang Injection with the clinical manifestation of skin allergy,some patients showed symptoms of fever,shaking,chest tightness,tachypnea and tinnitus. It is also found that dexamethasone or promethazine hydrochloride is effective to reverse the adverse reaction caused by Shenkang injection. Conclusion: The clinical use of Shenkang injection should be strictly in accordance with the instructions for use and observing patients' reaction. Stop medication in case of adverse reaction. The use of dexamethasone or promethazine hydrochloride can be effective to cure the adverse reaction.
出处
《贵阳医学院学报》
CAS
2015年第6期650-652,共3页
Journal of Guiyang Medical College