摘要
梅毒血清学固定是指梅毒患者经正规驱梅治疗后,血清滴度维持在低滴度不再下降的现象。其临床具有较高的发生率,并且发生机制尚不明确。近年来,国内外学者对此现象进行了大量研究总结,目前认为可能与梅毒治疗不规范、药物选择不当、梅毒的病期、治疗时梅毒血清抗体的基线滴度以及机体的免疫状态相关。梅毒血清学固定是梅毒复发、胎儿宫内感染以及发生神经心血管梅毒的危险因素。该文就其研究背景、概念,特别是病因、治疗方面进行综述。
Syphilis serofast（ SSF） is a medical phenomenon,i. e. the serum titer remains on a low level without further decline after treatment. It has a high clinical incidence while the pathogenesis is still not very clear. In recent years,scholars at home and abroad have conducted a number of studies on this phenomenon.It＇s currently considered that it may be associated with unstandardized syphilis treatment,improper drug selection,syphilis stage,syphilis serum antibody titers baseline during treatment,and the immune status of the body. SSF is a threat of recurrence,intrauterine infection,cardiovascular syphilis and neurosyphilis. Here is to make a review of the background and concepts of SSF,especially the cause and its treatment.
出处
《医学综述》
2015年第12期2154-2156,共3页
Medical Recapitulate
