摘要
目的了解普米克令舒联合孟鲁司特(二联疗法)治疗儿童慢性咳嗽的效果。方法慢性咳嗽病儿136例,随机分为对照组和观察组,观察组采用二联疗法治疗,对照组仅在睡前口服顺尔宁孟鲁司特钠片5mg。两组病儿均持续药物治疗1周。比较两组病儿治疗前后咳嗽频率、严重程度以及疗效。结果治疗后观察组的咳嗽频率评分、严重程度评分明显低于对照组,治疗前后评分差值明显大于对照组,差异有统计学意义(t=8.635~126.221,P〈0.05);观察组疗效优于对照组,差异有统计学意义(uc=2.715,P〈0.05)。结论二联疗法治疗儿童慢性咳嗽效果好,值得临床推广应用。
Objective To assess the efficacy of Pulmicort Respules(PR)combined with Montelukast(ML)-bigeminal therapy-in the treatment of chronic cough in children. Methods A total of 136 kids with chronic cough were enrolled and divided into observation group and control group.The sick kids in the observation group received bigeminal therapy,and those in the control group received only oral Montelukast Sodium(5mg)at bedtime.The treatment lasted one week for both groups.A comparison between before and after treatment in the two groups was done in terms of cough frequency,severity and efficacy. ResultsAfter therapy,the score of cough frequency,severity,and pre-and post-therapy difference score were notably lower than that in the control group,the differences were significant(t=8.635-126.221,P0.05),and the therapeutic effect was better in the observation group versus the control(uc=2.715,P0.05). Conclusion The bigeminal therapy is effective for chronic cough in children,it is worthy of clinical application.
出处
《青岛大学医学院学报》
CAS
2015年第4期491-492,共2页
Acta Academiae Medicinae Qingdao Universitatis