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血清降钙素原在AECOPD中抗感染治疗的指导意义 被引量:13

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摘要 目的探讨血清降钙素原(PCT)能否在慢性阻塞性肺疾病急性加重期(AECOPD)中抗生素治疗方面有指导意义。方法选入75例AECOPD患者,分成PCT组(n=40)和对照组(n=35)。对照组仅根据患者临床症状的缓解或消失决定抗生素的停用,而PCT组在对照组停药依据的基础上加上了血清PCT水平(PCT<0.25ng/mL)决定抗生素的停用。观察指标主要为抗生素治疗时间,住院时间,临床加重数,3个月内复发率、病死率、临床有效率。结果 PCT组的抗生素治疗时间、住院时间和3个月内再次住院率与对照组比较差异有统计学意义(P<0.05)。结论根据患者PCT水平指导抗感染策略在AECOPD患者中是安全有效的,能够降低抗生素的过度使用、减少患者复发率。
出处 《重庆医学》 CAS 北大核心 2015年第22期3111-3112,共2页 Chongqing medicine
基金 佛山市顺德区人口和卫生药品监督局科研立项(2013087)
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